Tissue expansion for correction of scars due to burn and other causes: A retrospective comparative study of various complications

Fochtmann, Alexandra; Keck, Maike; Mittlböck, Martina; Rath, Th-H.

doi:10.1016/j.burns.2012.10.020

Cited by 24 publications

(34 citation statements)

References 16 publications

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“…A tissue expander is known as a device especially designed to induce skin or tissue expansion in response to stress or to a given deformation for reconstructive/plastic surgeries . Keeping a tissue under constant tension may be resulted in skin stretching, which may change the extracellular matrix (ECM) organization and stimulate cell division, resulting in the formation of new tissues . Enlargement of soft tissue volume as well as its superficial area is a natural phenomenon, observed in obesity and pregnancy .…”

Section: Introductionmentioning

confidence: 99%

Poly (Ethylene Glycol)‐Based Hydrogels as Self‐Inflating Tissue Expanders with Tunable Mechanical and Swelling Properties

Jamadi

Shokrollahi

Houshmand

et al. 2017

Macromolecular Bioscience

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Tissue expansion is used by plastic/reconstructive surgeons to grow additional skin/tissue for replacing or repairing lost or damaged soft tissues. Recently, hydrogels have been widely used for tissue expansion applications. Herein, a self-inflating tissue expander blend composition from three different molecular weights (2, 6, and 10 kDa) of poly (ethylene glycol) diacrylate (PEGDA) hydrogel with tunable mechanical and swelling properties is presented. The in vitro results demonstrate that, of the eight studied compositions, P6 (PEGDA 6 kDa:10 kDa (50:50)) and P8 (PEGDA 6 kDa:10 kDa (35:65)) formulations provide a balance of mechanical property and swelling capability suitable for tissue expansion. Furthermore, these expanders can be compressed up to 60% of their original height and can be loaded and unloaded cyclically at least ten times with no permanent deformation. The in vivo results indicate that these two engineered blend compositions are capable to generate a swelling pressure sufficient to dilate the surrounding tissue while retaining their original shape. The histological analyses reveal the formation of fibrous capsule at the interface between the implant and the subcutaneous tissue with no signs of inflammation. Ultimately, controlling the PEGDA chain length shows potential for the development of self-inflating tissue expanders with tunable mechanical and swelling properties.

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Section: Introductionmentioning

confidence: 99%

Poly (Ethylene Glycol)‐Based Hydrogels as Self‐Inflating Tissue Expanders with Tunable Mechanical and Swelling Properties

Jamadi

Shokrollahi

Houshmand

et al. 2017

Macromolecular Bioscience

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“…Compared with traditional treatments mainly focusing on the coverage of defects, skin expansion offers the recovery of both appearance and function without donor site morbidity . However, the biggest obstacle in the application of skin expansion techniques is the inherent limited regenerative capability of local skin tissue …”

Section: Discussionmentioning

confidence: 99%

“…4,21,22 However, the biggest obstacle in the application of skin expansion techniques is the inherent limited regenerative capability of local skin tissue. 5,8,23,24 Stem cell application may be an effective solution due to the capability of differentiation and growth factor secretion. 13,25 Our recent studies have reported that topical transplantation of stem cells could be helpful in promoting expanded skin regeneration.…”

Section: Discussionmentioning

confidence: 99%

Intravenous transplantation of bone marrow mesenchymal stem cells could effectively promote vascularization and skin regeneration in mechanically stretched skin

et al. 2015

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“…The tissue expander concept was partial by Neumann in 1957, following avulsion is used for ear reconstruction. The early 1980s, breast, soft tissue and burn reconstruction has been popularized by Radovan (3,5,(8)(9)(10)(11)(12)(13)(14). The tissue expander has found widespread use in reconstructive surgery.…”

Section: Discussionmentioning

confidence: 99%

“…Tissue expansion is associated with a relatively high complication rate. In the literature has been found in the range of % 10 to 80 complication rate (14). The use of tissue expanders in the extremities is associated with a high complication rate (12).…”

Section: Discussionmentioning

confidence: 99%

Use with Tissue Expander Face, Scalp and Neck Reconstruction

et al. 2015

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The tissue expander has found widespread use in reconstructive surgery. The donor area is needed, the recipient site with similar characteristics (color, thickness, hair follicle) features, minimal scarring and leads to donor site morbidity. In our study, presented face, scalp and neck reconstruction results obtained with the use of expander. The face, scalp and neck areas expander was used to evaluate patients in the Plastic, Reconstructive and Aesthetic Surgery Department of Yüzüncü Yıl University. Age, gender, expander indication, defect or scar area localization, expander residential area, expander shape, volume, valve location (internalexternal), expansion time, major and minor complications were reviewed. 30 number expanders were used in 17 patients (8 male, 9 female patients). Expanders were used burn sequelae in 14 patients, tumor-related defects in 2 patients and due to giant hairy nevus in 1 patient. The expanders are scalp (19 cases), face (3 cases), supraclaviculer (7 cases) and the neck (1 case) has to be placed. In 4 of 17 patients (three major and one minor) complications were encountered. Use the expander is a good option especially in the reconstruction of soft tissue defects in the head and neck region. Yüz, baş ve boyun rekonstruksiyonunda doku genişletici kullanımıÖZET Doku genişletici rekonstruktif cerrrahide yaygın kullanım alanı bulmuştur. Donör saha duyulu, alıcı saha ile benzer karakterde (renk, kalınlık, saç folikülü olup olmama gibi) özelliklere sahiptir, minimal skar ve donör saha morbiditesine neden olur. Çalışmamızda, yüz, baş ve boyun rekonstruksiyonunda doku genişletici kullanımı ile elde edilen sonuçlar sunuldu. Yüzüncü Yıl Üniversitesi Plastik, Rekonstrüktif ve Estetik Cerrahi Anabilim Dalı'nda yüz, scalp ve boyun bölgelerinde doku genişletici kullanılan hastalar değerlendirildi. Yaş, cinsiyet, doku genişletici endikasyonu, defekt veya skar lokalizasyonu, doku genişletici yerleşim alanı, şekli, volumü, ekspansiyon sonrası volüm, ekspansiyon süresi, major ve minor komplikasyonlar gözden geçirildi. 30 adet doku genişletici 17 hastada kullanıldı (8 erkek, 9 bayan). Doku genişletici 14 hastada yanık sekeli, 2 hastada tumöre bağlı defekt ve 1 hastada dev kıllı nevus nedeniyle kullanıldı. Doku genişleticiler baş (19 olgu), yüz (3 olgu), supraklavikuler (7 olgu) ve boyun (1 olgu) olacak şekilde yerleştirildi. 17 olgunun 4 tanesinde (3 major ve 1 minör) komplikasyon ile karşılaşıldı. Doku genişletici kullanımı özellikle baş boyun bölgesi yumuşak doku defektlerinin rekonstrüksiyonunda iyi bir seçenektir.Anahtar kelimeler: Doku genişletici, yüz, baş, boyun, rekonstrüksiyon.

show abstract

Tissue expansion for correction of scars due to burn and other causes: A retrospective comparative study of various complications

Cited by 24 publications

References 16 publications

Poly (Ethylene Glycol)‐Based Hydrogels as Self‐Inflating Tissue Expanders with Tunable Mechanical and Swelling Properties

Poly (Ethylene Glycol)‐Based Hydrogels as Self‐Inflating Tissue Expanders with Tunable Mechanical and Swelling Properties

Intravenous transplantation of bone marrow mesenchymal stem cells could effectively promote vascularization and skin regeneration in mechanically stretched skin

Use with Tissue Expander Face, Scalp and Neck Reconstruction

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