Tissue Engineering in Periodontal Regeneration

Iranparvar, Aysel; Nozariasbmarz, Amin; DeGrave, Sara; Tayebi, Lobat

doi:10.1007/978-3-030-21583-5_14

Cited by 3 publications

(2 citation statements)

References 174 publications

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“…The stem cells of periodontal ligament, dental pulp, and apical papilla can differentiate into osteoblasts, chondrocytes, or neurocytes depending on the nature of trigger and medium in vitro. Thus, the different rheological properties of HA-based gels can trigger different cellular responses [2,29,30].…”

Section: Modification Of Native Hamentioning

confidence: 99%

“…It can be used as a standalone material to trigger certain cellular functions, a 3D gel scaffold for cells growth and differentiation, gel scaffold working as a physical barrier between soft and hard tissue, gel scaffold containing growth factors or other natural factors (bone morphogenic factors, fibroblast growth factors, platelet-derived growth factors) released over certain time and/or concentrations, carrier for drugs ensuring their sustained release, and co-material with other biological (fibrin, collagen, chondroitin sulphate, hydroxy apatite), natural (cellulose, chitin, starch, alginate, silk), or synthetic materials for enhanced function of either entity. HA applications in dental procedures vary widely, and one should always keep in mind the four essential factors (cell viability, type of cellular trigger, angiogenesis, physicochemical characteristics of the scaffold) required for regeneration or wound healing as evaluation tools when exploring the possible applications or expected outcome results of a natural biomaterial [30,36]. Some examples on HA uses in dentistry include:…”

Section: Exact Clinical and Cellular Effect (If Known)mentioning

confidence: 99%

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Biological molecules in dental applications: hyaluronic acid as a companion biomaterial for diverse dental applications

Al-Khateeb¹,

Olszewska-Czyż

2020

Heliyon

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The application of hyaluronic acid (HA) in dental treatments is relatively new, and modified-HA products can be vastly different from each other. This study aims to provide a basis for bridging specific characteristics of HA with its potential applications in dental treatments, evaluating and comparing different types of HA products and for future research on HA applications in dentistry. Data sources: Information from the existing literature on HA applications has been cited. Study selection: Furthermore, this study is specifically oriented to provide oral health care providers with a scientific basis for HA use along with the clinical aspects of HA. Conclusions: Outcomes from existing and future studies cannot be generalised for HA use in dental applications. Therefore, we have proposed a scheme to bridge HA specific characteristics to its applications in dental treatments and compare different HA products used for the same clinical application to identify the most suitable one. Clinical significance: Highlighting the use of HA in dental treatments and providing a basis for developing new methods, protocols, and products specifically oriented for dentistry.

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Section: Modification Of Native Hamentioning

confidence: 99%

Section: Exact Clinical and Cellular Effect (If Known)mentioning

confidence: 99%