Abstract:Introduction Tissue engineering aims to combine isolated cells, engineered materials and small molecule biochemical factors to generate neotissues with specific form and function to replace or repair damaged or degenerate native tissue. Intervertebral disc (IVD) degeneration directly causes back pain, and understanding how to regenerate this tissue may help alleviate this costly global problem. Several studies have combined isolated nucleus pulposus (NP) disc cells with novel scaffold materials to produce prom… Show more
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