Tissue Doppler Septal Tei Index Indicates Severity of Illness in Pediatric Patients With Congestive Heart Failure

Mejia, Aura A Sanchez; Simpson, Kathleen E.; Hildebolt, Charles F.; Pahl, Elfriede; Matthews, Kathleen L.; Rainey, Cheryl A.; Canter, Charles E.; Jay, Patrick Y.; Johnson, Mark C.

doi:10.1007/s00246-013-0794-1

Cited by 11 publications

(9 citation statements)

References 29 publications

(46 reference statements)

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“…From the findings of the present study, children with CHF had reduced cardiac function parameters detected by TDI that included reduced left ventricular ejection fraction (LVEF), left ventricular fractional shortening (LVFS), and ejection time (ET), and increased MPI TDI and MPI TDI-R. The findings in children with CHF probably affected both ventricular systolic and diastolic dysfunction as has been previously shown [ 15 ]. In this study, receiver-operating characteristic (ROC) curve analysis showed that the MPI TDI-R had a sensitivity of 67.5%, and a specificity of 97.5%, which was better than for MPI TDI.…”

Section: Discussionsupporting

confidence: 80%

R-Wave Modified Tissue Doppler Imaging Myocardial Performance Index for the Assessment of Cardiac Function in Children with Congestive Heart Failure: A Feasibility Study

2018

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BackgroundThe aim of this study was to evaluate the feasibility of an R-wave modified tissue Doppler imaging (TDI) myocardial performance index (MPI), or MPI TDI-R, for the assessment of cardiac function in children with congestive heart failure (CHF).Material/MethodsForty children with CHF and 40 normal children were evaluated using the modified pediatric Ross heart failure grading system. TDI recorded the spectrum of diastolic function at the mitral valve annulus to measure the MPI. Twelve-lead electrocardiogram (ECG) measured the R-wave in the QRS complex, resulting in the modified MPI TDI-R. Correlation between the MPI TDI-R, other echocardiographic indices, and the Ross heart failure grades were analyzed, with reproducibility analysis.ResultsCompared with normal children, the MPI TDI and MPI TDI-R were significantly increased in the pediatric CHF group (P<0.01). The MPI TDI-R was significantly correlated with other indices of cardiac function and Ross grading for CHF in children (r=0.769). The MPI TDI-R showed good correlation with the findings of the MPI TDI, calculated by traditional methods. Receiver-operating characteristic (ROC) curve analysis showed that the MPI TDI-R had a sensitivity of 67.5%, and a specificity of 97.5%. The reproducibility of the MPI TDI-R was confirmed to be superior when compared with the non-modified MPI TDI.ConclusionsThis feasibility study showed that the modified MPI TDI-R, formed by combining the MPI TDI with synchronous surface ECG measurements, was simple to perform, reproducible, and provided a specific index for the assessment of cardiac function in children with CHF.

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Section: Discussionsupporting

confidence: 80%

R-Wave Modified Tissue Doppler Imaging Myocardial Performance Index for the Assessment of Cardiac Function in Children with Congestive Heart Failure: A Feasibility Study

2018

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“…In these severe categories of bronchial asthma, conventional echocardiography started to detect left ventricular diastolic dimension and right ventricular systolic pressure changes. In a study done by Sanchez Mejia et al, TDI of the septal Tei index was found to be a more sensitive indicator of the disease severity than the TDI free wall Tei index. The enhanced sensitivity of the septal Tei index may reflect the combined dysfunction of the left and right ventricles.…”

Section: Discussionmentioning

confidence: 92%

Assessment of lateral mitral, septal and tricuspid myocardial performance indices by tissue Doppler imaging in asthmatic children

Elseify

Alsharkawy

Al-Fahham

et al. 2018

Clinical Respiratory J

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Abbreviations: FEV1, expiratory volume in the 1st second; FVC, forced vital capacity; MMEF, forced expiratory volume in the 1st second/ forced vital capacity ratio, maximum mid-expiratory flow75/25; PEF, peakexpiratory flow. AbstractIntroduction: Recurrent hypoxia makes asthmatics at risk for pulmonary hypertension and ventricular dysfunction. Early stages of these cardiovascular diseases cannot be detected by conventional echocardiography. Tissue Doppler imaging has been introduced recently as a more sensitive and more accurate tool for investigating cardiovascular diseases. Objective: Investigating ventricular functions in asymptomatic asthmatic children using tissue Doppler echocardiography. Method: Fifty asthmatic children and 50 controls were examined by conventional echocrdiography. Tissue Doppler echocardiography was performed to measure the myocardial performance (Tei) index at the lateral mitral, septal and tricuspid annuli. Results: Septal Tei indices among patients and uncontrolled asthmatics were significantly higher than healthy subjects and controlled asthmatics, respectively (P < 0.05).Septal and tricuspid Tei indices were significantly higher among severe asthmatics and patients with concomitant nasal allergy than those with mild asthma and those without concomitant nasal allergy, respectively (P < 0.05). Septal Tei index correlated negatively with daily inhaled corticosteroid dose (r = -0.412, P = 0.003) and forced expiratory volume in the 1st second/forced vital capacity (r = -0.877, P < 0.001). Lateral Tei index correlated positively with the patient age (r = 0.312, P = 0.027) and duration of asthma (r = 0.359, P = 0.011). Conclusion: Tei index can detect subclinical ventricular dysfunction in asthmatics and is affected by asthma duration, control and severity. It can be used for future scoring of asthma severity. Septal annulus seems to be the best location for assessing Tei index in asthmatics. K E Y W O R D S asthma, cardiology, chest, echocardiology, pediatric, spirometry, Tei index | 2677 ELSEIFY ET AL. How to cite this article: Elseify MY, Alsharkawy AA, Al-Fahham MM, ElHady MM. Assessment of lateral mitral, septal and tricuspid myocardial performance indices by tissue Doppler imaging in asthmatic children. Clin Respir J.

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“…The Tei index combines the systolic and diastolic functions of ventricles in an index of global myocardial performance. 14) It correlates with the severity and clinical outcome in children with cardiac disease. 14) 28) The Tei index could be used as an accurate tool for estimating myocardial function in KD patients.…”

Section: Discussionmentioning

confidence: 99%

“… 14) It correlates with the severity and clinical outcome in children with cardiac disease. 14) 28) The Tei index could be used as an accurate tool for estimating myocardial function in KD patients. 29) According to Ajami et al 30) after IVIG treatment in KD patients, the Tei index changed from 0.43±0.08 to 0.35±0.06.…”

Section: Discussionmentioning

confidence: 99%

“…Tissue Doppler imaging (TDI) may be a superior method to measure the Tei index in children because it is less affected by heart rate variability. 14) The myocardial performance index (Tei index) evaluates global left ventricle (LV) systolic and diastolic function. It is correlated with severity and clinical outcome in children with cardiac disease.…”

Section: Introductionmentioning

confidence: 99%

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Cardiac Function in Kawasaki Disease Patients with Respiratory Symptoms

et al. 2015

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Background and ObjectivesRespiratory symptoms are often observed in children with Kawasaki disease (KD) during the acute phase. The association of respiratory viruses in children with KD was investigated using multiplex reverse transcriptase-polymerase chain reaction (RT-PCR) and tissue Doppler echocardiography.Subjects and Methods138 KD patients were included from January 2010 to June 2013. We compared 3 groups (group 1: n=94, KD without respiratory symptoms; group 2: n=44, KD with respiratory symptoms; and group 3: n=50, febrile patients with respiratory symptoms). Laboratory data were obtained from each patient including N-terminal pro-brain natriuretic peptide (NT-proBNP). Echocardiographic measurements were compared between group 1 and group 2. RT-PCR was performed using nasopharyngeal secretion to screen for the presence of 14 viruses in groups 2 and 3.ResultsThe incidence of KD with respiratory symptoms was 31.8%. The duration of fever was significantly longer, and coronary artery diameter was larger in group 2 than in group 1. Tei index was significantly higher and coronary artery diameter larger in group 2 than group 1. Coronary artery diameter, C-reactive protein levels, platelet count, alanine aminotransferase levels, and NT-pro BNP levels were significantly higher and albumin levels lower in group 2 compared with group 3.ConclusionNT-pro BNP was a valuable diagnostic tool in differentiating KD from other febrile viral respiratory infections. Some viruses were more frequently observed in KD patients than in febrile controls. Tei index using tissue Doppler imaging was increased in KD patients with respiratory symptoms.

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Tissue Doppler Septal Tei Index Indicates Severity of Illness in Pediatric Patients With Congestive Heart Failure

Cited by 11 publications

References 29 publications

R-Wave Modified Tissue Doppler Imaging Myocardial Performance Index for the Assessment of Cardiac Function in Children with Congestive Heart Failure: A Feasibility Study

R-Wave Modified Tissue Doppler Imaging Myocardial Performance Index for the Assessment of Cardiac Function in Children with Congestive Heart Failure: A Feasibility Study

Assessment of lateral mitral, septal and tricuspid myocardial performance indices by tissue Doppler imaging in asthmatic children

Cardiac Function in Kawasaki Disease Patients with Respiratory Symptoms

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