Tissue doppler imaging predicts improved systolic performance and reversed left ventricular remodeling during long-term cardiac resynchronization therapy

Søgaard, Peter; Egeblad, Henrik; Kim, Won Yong; Jensen, Henrik; Pedersen, Anders Kirstein; Kristensen, Bent Bruun; Mortensen, Peter Thomas

doi:10.1016/s0735-1097(02)02010-7

Cited by 548 publications

(340 citation statements)

References 18 publications

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“…5,11 The technique of TDI was also combined with SRI to search for PSS, or delayed longitudinal contraction. 10,23 The presence of PSS in the basal LV segments was found to correlate with the gain in ejection fraction in 25 patients receiving CRT. 10 In that study, ejection fraction (but not volumetric data) was used as an indicator of reverse remodeling.…”

Section: Tdi Pss Sri and Reverse Remodelingmentioning

confidence: 97%

“…2,5,9 This might be explained by the fact that direct assessment of systolic asynchrony rather than QRS duration is the key for selecting appropriate patients for CRT and predicting a favorable response. 5,10 Echocardiography has been the cornerstone for serial assessment of systolic asynchrony, among which tissue Doppler imaging (TDI) has been most widely used. 5,10 -13 The main quantitative parameters derived from TDI measured the difference or variation in time to peak regional contraction between 2 or more LV segments, 4,5,12,13 the presence of postsystolic shortening (PSS), 10 and possibly strain-rate imaging (SRI).…”

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confidence: 99%

“…5,9,10 In addition, the pattern of systolic asynchrony may be different between ischemic and nonischemic causes of heart failure. 10 This may affect the predictive value of the echocardiographic tool chosen. Therefore, the aims of the study were to compare the relative predictive values of TDI-, PSS-, and SRI-derived parameters on the prediction of LV reverse remodeling and to explore whether there is any difference in such predictive value between ischemic and nonischemic heart failure after CRT.…”

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confidence: 99%

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Tissue doppler imaging is superior to strain rate imaging and postsystolic shortening in the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy

Yu¹,

Fung²,

Zhang³

2004

ACC Current Journal Review

168

291

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Background-A number of noninvasive techniques have been used to predict the effectiveness of cardiac resynchronization therapy (CRT) in heart failure patients, in particular left ventricular (LV) reverse remodeling. This study compared the relative predictive values of tissue Doppler imaging (TDI) and strain-rate imaging (SRI) parameters for LV reverse remodeling in patients who received CRT and examined for potential differences in ischemic (nϭ22) and nonischemic (nϭ32) heart failure. Methods and Results-TDI and SRI were performed at baseline and 3-month follow-up. Eighteen parameters of intraventricular and interventricular asynchrony based on the time to peak myocardial contraction (Ts) and time to peak strain rate (Tsr) were compared, along with postsystolic shortening (PSS). Reverse remodeling with reduction of LV end-diastolic and end-systolic volumes and gain in ejection fraction (all PϽ0.001) was observed in the whole study population. The standard deviation of Ts of 12 LV segments (Ts-SD) is the most powerful predictor of reverse remodeling in both the ischemic (rϭϪ0.65, PϽ0.001) and nonischemic (rϭϪ0.79, PϽ0.001) groups. The PSS of 12 LV segments was a good predictor only for the nonischemic (rϭϪ0.64, PϽ0.001) but not the ischemic (rϭ0.32, PϭNS) group. However, parameters of SRI and interventricular asynchrony failed to predict reverse remodeling. By multiple regression analysis, independent parameters included Ts-SD in both groups (PϽ0.005) and PSS of 12 LV segments in the nonischemic group (Pϭ0.03). The area of the receiver operating characteristic curve was largest for Ts-SD (0.94; CIϭ0.88 to 1.00). Conclusions-Ts-SD is the most powerful predictor of LV reverse remodeling and was consistently useful for ischemic and nonischemic heart failure. However, PSS is useful only for nonischemic pathogenesis, whereas the role of SRI parameters was not supported by the present study.

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Section: Tdi Pss Sri and Reverse Remodelingmentioning

confidence: 97%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Tissue doppler imaging is superior to strain rate imaging and postsystolic shortening in the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy

Yu¹,

Fung²,

Zhang³

2004

ACC Current Journal Review

168

291

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“…Nevertheless it is reported that similar results with colored Doppler could be obtained (1). With the measurement of tissue displacement, in other words tissue tracking imaging, the visual and quantitative amount of tissue motion can be interpreted in millimeters-centimeters in a relatively easier way (33)(34)(35)(36). As strain and strain rate imaging are not affected by impulsion-traction and translation, they may provide better differentiation of mechanical delay (37,38).…”

Section: Discussionmentioning

confidence: 99%

Acute effect of primary percutaneous coronary intervention on left ventricular dyssynchrony in ST-segment elevation myocardial infarction

İnci¹,

Karakelleoğlu²,

Taş³

et al. 2014

Anadolu Kardiyol Derg

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Objective: The aim of this study was to prospectively evaluate the effect of percutaneous coronary intervention in the acute period on left ventricular dyssynchrony in ST-segment elevation myocardial infarction patients by using Tissue Synchronization Imaging. Methods: Forty-four ST-segment elevation myocardial infarction (MI) patients (29 male, 15 female), who were admitted within the first 12 hours of chest pain symptoms, were enrolled in the study. According to the localization of MI, the patients were divided into groups as anterior MI (n=26) and inferior MI (n=18). All echocardiography measurements were taken just before percutaneous coronary intervention (PCI) and following PCI at a mean of 3-6 days. They were assessed according to the time to reach the peak systolic velocity, which was calculated by the tissue synchronization imaging method from four pairs of non-apical alternate segments. The difference between the duration to reach the peak systolic velocity in alternate segments was regarded as left ventricle dyssynchrony and the results were compared. Results: In the anterior MI group, basal anterior (p<0.01), mid-anterior segment (p<0.01) and basal septal segment (p<0.01); in the inferior MI group, the basal septal segment (p=0.02), mid-septal segment (p=0.02), and basal and mid-inferior segment (p<0.01) values were significantly lower in the post-PCI measurements when compared to the measurements taken prior to PCI. In both groups, the intraventricular dyssynchrony indices of the basal anterior-basal inferior (p<0.01), mid-anterior-mid-inferior (p<0.01) segments were found to be significantly lower in the post-PCI period when compared to the pre-PCI period. Conclusion: It was found that percutaneous coronary intervention in patients with ST-elevation significantly decreases the degree of LV dyssynchrony in the acute period. (Anadolu Kardiyol Derg 2014; 14: 591-8)

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“…Both echocardiography and MRI are used to quantify mechanical dyssynchrony. While several measures of mechanical dyssynchrony are commonly used in ultrasound, such as tissue Doppler imaging (velocity [9,10], strain [11]) or 3D-echo (volume [12,13]), MRI predominantly focuses on circumferential strain [6,14]. Myocardial strain is probably a more robust parameter for assessing mechanical dyssynchrony than regional wall motion or velocity, as it is less affected by overall heart motion and tethering [15].…”

Section: Introductionmentioning

confidence: 99%

Relation between three-dimensional echocardiography derived left ventricular volume and MRI derived circumferential strain in patients eligible for cardiac resynchronization therapy

Rüssel

Dijk

Kleijn

et al. 2008

Int J Cardiovasc Imaging

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Objectives To compare regional left ventricular (LV) volume curves obtained with real time three-dimensional echocardiography (RT3DE) with two-dimensional circumferential strain curves obtained by MRI in cardiac resynchronization therapy candidates. Background Several methods using either ultrasound or MRI are used to quantify mechanical dyssynchrony (MD). Theoretically, LV volume and circumferential strain seem related, since both measures are connected to the radius of the ventricle. Methods In 21 patients with chronic heart failure, RT3DE and tagged MRI were performed subsequently. Regional LV volume was computed from the ultrasound images. From the MR images, regional circumferential strain was calculated. Cross-correlations with time lags of 1% of the cardiac cycle were performed to compare the curves in corresponding LV segments. Furthermore, peak septal to lateral (SL) delays were compared between modalities. Results High correlations were found between the curves (r 2 = 0.65 ± 0.19), but regional differences in time delay between modalities were observed. In the septum, the volume curve was earlier than the strain curve by 1.8 ± 17.0 time-lags (n.s.), while in the lateral wall, the volume curve was earlier by 3.3 ± 12.0 time-lags (P \ 0.02). There was a non-significant difference between SL delays in the two modalities (volume: -1.0 ± 8.6%, strain: 3.0 ± 12.7%, P = 0.17, a positive sign indicates that the lateral wall is delayed). Conclusions High correlations were observed between both modalities, but regional differences in time-delay were found. This is possibly inherent to the method of echocardiographic volume calculation and hampers the comparison of both measures for the quantification of MD.

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Tissue doppler imaging predicts improved systolic performance and reversed left ventricular remodeling during long-term cardiac resynchronization therapy

Abstract: Cardiac resynchronization significantly improved LV function and reversed LV remodeling during long-term follow-up. Patients likely to benefit from CRT can be identified by TDI before implantation of a biventricular pacemaker.

Cited by 548 publications

References 18 publications

Tissue doppler imaging is superior to strain rate imaging and postsystolic shortening in the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy

Tissue doppler imaging is superior to strain rate imaging and postsystolic shortening in the prediction of reverse remodeling in both ischemic and nonischemic heart failure after cardiac resynchronization therapy

Acute effect of primary percutaneous coronary intervention on left ventricular dyssynchrony in ST-segment elevation myocardial infarction

Relation between three-dimensional echocardiography derived left ventricular volume and MRI derived circumferential strain in patients eligible for cardiac resynchronization therapy

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