Tissue Doppler‐derived atrial dyssynchrony predicts new‐onset atrial fibrillation during hospitalization for <scp>ST</scp>‐elevation myocardial infarction

Ibrahim, Ismail Mohamed; Hassanin, Mesbah Taha; Zaki, Manar Moustafa El

doi:10.1111/echo.14486

Cited by 4 publications

(5 citation statements)

References 40 publications

(65 reference statements)

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“…In the present study, hypertension was significantly higher in New-onset atrial fibrillation (77.2% vs. 48.3%, P value =0.012) and LDL significantly higher in New-onset atrial fibrillation (127.5 ± 10.2 vs. 121.6 ±10.263, P value=0.012). Our results are compatible with a study reported that the group with NOAF showed significantly higher prevalence of hypertension (P = .049) (8) . In the present study, conventional echocardiography data were insignificantly different between both groups except LAVI max which was significantly higher in New-onset atrial fibrillation (P value=0.024).…”

Section: A) B)supporting

confidence: 93%

“…In the present study, conventional echocardiography data were insignificantly different between both groups except LAVI max which was significantly higher in New-onset atrial fibrillation (P value=0.024). Our results agree with those documented by a study showed that indexed left atrial maximum volume (LAVI max ), left atrial dyssynchrony, and inter-atrial dyssynchrony were significantly higher in NOAF group (P < 0.001) (8). In contrast to this observation, other studies failed to demonstrate any predictive value of LAVI max in the acute phase after STEMI (9,10) .…”

Section: A) B)supporting

confidence: 92%

“…The authors stated by using ROC curve analysis that inter-atrial dyssynchrony showed the highest diagnostic performance (AUC 85%, 95% CI: 0.77-0.94, P < .001). A cutoff value at 23.8 ms showed a good validity for predicting NOAF with a sensitivity of 93.8% and a specificity of 68.1% (8) . In the present study, hypertension was significantly higher in New-onset atrial fibrillation (77.2% vs. 48.3%, P value =0.012) and LDL significantly higher in New-onset atrial fibrillation (127.5 ± 10.2 vs. 121.6 ±10.263, P value=0.012).…”

Section: A) B)mentioning

confidence: 89%

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Prediction of AF in ACS Patients Using Different Antiplatelets by Tissue Doppler Derived Atrial Dyssynchrony

Ebaid,

Elrabbat,

Kamel

et al. 2023

Benha Medical Journal

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Background: Acute coronary syndromes (ACS) are one of the major causes of mortality and morbidity worldwide. Current guidelines recommend dual antiplatelet therapy in patients with ACS. This study aimed to predict AF in ACS patients using ticagrelor or clopidogrel by tissue Doppler derived atrial Dyssynchrony and to assess the outcome morbidity and mortality in each group. Methods: This was an observational, case series, single center study, was carried out at coronary care unit at "Benha University hospital" on 200 patients with ACS (STEMI & NSTE-ACS), 100 of the patients used ticagrelor and the other 100 patients used clopidogrel, in the period from June 2022 to December 2022. Results: The incidence of AF was insignificantly different between the studied groups. LAVI max and Mitral regurgitation was significantly higher in New-onset AF patients (P value=0.024, 0.001 respectively). Tissue Doppler imaging data (Lateral mitral P-A' interval, septal mitral P-As interval, tricuspid P-A' interval, LA Dyssynchrony and Interatrial Dyssynchrony) were significantly higher in New-onset AF patients (P value<0.05). LA Dyssynchrony can significantly predict the incidence of AF with AUC 0.704 (95% CI: 0.636 -0.766) and P value = 0.008, at cut off value >7.792 ms, with 68.2 % sensitivity, 63.5 % specificity, 18.7 PPV and 94.2 NPV. LV GLS was significantly lower in New-onset AF patients (P value =0.035). Conclusion: Our study showed that there was no significant difference in electro-echocardiographic AF predictors such as PWD, LAVI max, left atrial dyssynchrony and interatrial dyssynchrony in ACS patients who received ticagrelor or clopidogrel.

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Section: A) B)supporting

confidence: 93%

Section: A) B)supporting

confidence: 92%

Section: A) B)mentioning

confidence: 89%

See 1 more Smart Citation

Prediction of AF in ACS Patients Using Different Antiplatelets by Tissue Doppler Derived Atrial Dyssynchrony

Ebaid,

Elrabbat,

Kamel

et al. 2023

Benha Medical Journal

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“…We selected the median value of LIAEMD for comparison. This selection was supported by evidence provided by previous investigations, according to which the mean of LIAEMD in control subjects ranges between 17 ms and 23 ms The case groups of these studies were comprised of patients with induced AF in invasive electrophysiology study, patients with paroxysmal AF, hypertensive patients with paroxysmal AF, and patients with acute myocardial infarction complicated with new‐onset AF . It is also worthy of note that LIAEMD was significantly statistically different between the control and case groups of these studies.…”

Section: Discussionmentioning

confidence: 58%

Determinants of left intra‐atrial electromechanical delay as evaluated by tissue Doppler imaging in candidates for coronary artery bypass graft surgery

Etemad

Hosseinsabet

2020

Echocardiography

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Objectives Inhomogeneity in the atrial conduction time is a predisposing factor for atrial fibrillation. The aim of our study was to determine the independent determinants of the left intra‐atrial electromechanical delay (LIAEMD) as a marker of left atrial (LA) dyssynchrony in candidates for coronary artery bypass graft surgery (CABGS). Methods This prospective cross‐sectional study recruited 516 consecutive candidates for CABGS. Via the pulsed‐wave tissue Doppler imaging modality in echocardiography, the times between the P wave and the peak of the a′ wave at the septal and lateral mitral annuli were measured and the difference between these times was considered to be LIAEMD. Additionally, clinical and laboratory data on each patient were gathered. The odds ratio for an increased LIAEMD was calculated in patients with and without diabetes in univariate and multivariate analyses. Results The multivariable analysis revealed that in the patients without diabetes, obesity, calcium‐channel blocker usage, an increased maximal LA volume, and a decreased lateral e′/a′ ratio and in the diabetic patients, diuretic usage and a decreased lateral e′/a′ ratio were independently correlated with an increased likelihood of LIAEMD occurrence (P < .05). Conclusions In our study on CABGS candidates, in the patients without diabetes, obesity, an increased maximal LA volume, calcium‐channel blocker usage, and a decreased lateral e′/a′ ratio and in the diabetic patients, diuretic usage and a decreased lateral e′/a′ ratio independently determined increased LIAEMD. The prevention or treatment of factors that are detrimental to the LA electromechanical function may be helpful for the preservation of the LA electromechanical integrity.

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“…Determining predictors of NOAF has been an important focus of research. Previous studies have proposed older age, 20 and comorbidities, 4 such as hypertension, 21 diabetes mellitus, 19 culprit lesion site, 13 CKD, 5 and neutrophil/lymphocyte ratio. 22 Rene et al 18 reported age, and BMI as independent predictors for the development of AF following MI.…”

Section: Discussionmentioning

confidence: 99%

Incidence and predictors of new‐onset atrial fibrillation in ST‐elevation myocardial infarction: A single‐center study

Zarei,

Bozorgi,

Khoshfetrat

et al. 2024

Health Science Reports

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Background and AimsAtrial fibrillation (AF) is a common arrhythmia that occurs following ST‐elevation myocardial infarction (STEMI) and can significantly impact clinical outcomes. We investigated the incidence and predictors of AF following STEMI in patients, as well as its association with major adverse cardiac and cerebrovascular events (MACCE).MethodsWe conducted a retrospective cohort study, including all STEMI patients who presented under code 247 to Tehran Heart Center between 2016 and 2020 and completed a 1‐year follow‐up. Patients were divided into two groups based on the development of AF during follow‐up, and their baseline and clinical characteristics were compared. We used multivariable regression models to identify predictors of MACCE.ResultsOut of 3647 STEMI patients, 84 (2.3%) developed new‐onset AF (NOAF). Patients with AF were significantly older and had lower levels of total and low‐density lipoprotein cholesterol, triglyceride, and hemoglobin, but higher levels of fasting blood sugar and creatinine. AF patients were also more likely to have a history of hypertension, chronic kidney disease (CKD), congestive heart failure, and cerebrovascular accidents. The multivariable logistic regression model identified the CHA2DS2‐VASc score and CKD as independent predictors of NOAF following primary percutaneous coronary intervention. Furthermore, the incidence of MACCE was higher in the AF group, and AF independently predicted MACCE with a hazard ratio of 2.766.ConclusionThe CHA2DS2‐VASc score and the presence of CKD can serve as useful predictors of NOAF among patients with STEMI. Early detection and appropriate management are crucial to improve outcomes.

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Tissue Doppler‐derived atrial dyssynchrony predicts new‐onset atrial fibrillation during hospitalization for ST‐elevation myocardial infarction

Cited by 4 publications

References 40 publications

Prediction of AF in ACS Patients Using Different Antiplatelets by Tissue Doppler Derived Atrial Dyssynchrony

Prediction of AF in ACS Patients Using Different Antiplatelets by Tissue Doppler Derived Atrial Dyssynchrony

Determinants of left intra‐atrial electromechanical delay as evaluated by tissue Doppler imaging in candidates for coronary artery bypass graft surgery

Incidence and predictors of new‐onset atrial fibrillation in ST‐elevation myocardial infarction: A single‐center study

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