2017
DOI: 10.11569/wcjd.v25.i35.3123
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Tissue distribution of main active components of Fagopyrum cymosum extracts in mice with ulcerative colitis

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“…In response to oxidized oil, the proinflammatory cytokine IL-6 was significantly increased ( Rose-John, 2018 ). However, mRNA expression of IL-6 in jejunal mucosa treated with oxidized oils were markedly reduced after treatment with F. dibotrys; this compound had anti-inflammatory protection for ulcerative colitis ( Ge et al., 2017 ) and it stimulated expression of IL-22 in jejunal mucosa, which could alleviate intestinal epithelial oxidative stress and promote repair ( Wan and Pan, 2016 ).…”
Section: Discussionmentioning
confidence: 99%
“…In response to oxidized oil, the proinflammatory cytokine IL-6 was significantly increased ( Rose-John, 2018 ). However, mRNA expression of IL-6 in jejunal mucosa treated with oxidized oils were markedly reduced after treatment with F. dibotrys; this compound had anti-inflammatory protection for ulcerative colitis ( Ge et al., 2017 ) and it stimulated expression of IL-22 in jejunal mucosa, which could alleviate intestinal epithelial oxidative stress and promote repair ( Wan and Pan, 2016 ).…”
Section: Discussionmentioning
confidence: 99%