Tissue damage and concentration at the injection site after intramuscular injection of chemotherapeutics and vehicles in pigs

Rasmussen, Folke; Svendsen, Ove

doi:10.1016/s0034-5288(18)33479-9

Cited by 45 publications

(14 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As streptocillin As streptocillin 4 L. BLOM AND F. RASMUSSEN that observed in cattle and swine (Rasmussen and Hogh, 1971;Svendsen, 1972;Rasmussen et at., 1973;Steiness et al, 1974;Rasmussen and Ladefoged, 1974;Rasmussen and Svendsen, 1976).…”

Section: As Tetracyclinesmentioning

confidence: 98%

“…Any substantial or systematic reproduction, redistribution, reselling, loan, sub-licensing, systematic supply, or distribution in any form to anyone is expressly forbidden. Terms & Conditions of access and use can be found at http://www.tandfonline.com/page/termsand-conditions INTRODUCTION A number of papers describing tissue damage in cattle and swine after intramuscular injection of preparations containing antibiotics or chemotherapeutics have been published (Gilbert et ah, 1971;Rasmussen and Hogh, 1971;Svendsen, 1972;Rasmussen et al, 1973;Rasmussen and Ladefoged, 1974;Rasmussen and Svendsen, 1976). Damage to the tissue of hens and turkeys following injections of streptomycin or dihydrostreptomycin has also been observed by the Institute for Poultry Diseases, Copenhagen.…”

Section: Please Scroll Down For Articlementioning

confidence: 99%

“…To cite this article: L. Blom & F. Rasmussen (1976) Tissue damage at the injection site after intramuscular injection of drugs in hens, British Poultry Science, 17:1, 1-4, DOI: 10.1080/00071667608416242…”

mentioning

confidence: 99%

See 2 more Smart Citations

Tissue damage at the injection site after intramuscular injection of drugs in hens

Blom¹,

Rasmussen²

1976

British Poultry Science

View full text Add to dashboard Cite

show abstract

Section: As Tetracyclinesmentioning

confidence: 98%

Section: Please Scroll Down For Articlementioning

confidence: 99%

See 1 more Smart Citation

Tissue damage at the injection site after intramuscular injection of drugs in hens

Blom¹,

Rasmussen²

1976

British Poultry Science

View full text Add to dashboard Cite

show abstract

“…The potential for injection site depots is defined. Injection site residue problems are often involved in long withdrawal periods (Rasmussen and Svendsen, 1976). 7.…”

Section: Application Of Pharmacokinetics To the Drug Residue Problemmentioning

confidence: 99%

“…6. Indications of drug depot problems-for example, injection site, problems with oxytetracycline (Pilloud, 1973) and sulfonamides (Rasmussen and Svendsen, 1976). 7.…”

Section: Slaughter Animals and Measure Tissue Concentrations At The Pmentioning

confidence: 99%

Application of pharmacokinetic methods to the drug residue profile

Mercer

Baggot²,

Samś

1977

Journal of Toxicology and Environmental Health

View full text Add to dashboard Cite

A pharmacokinetic approach to the delineation of a drug residue profile in food-producing animals has been presented. It is recognized that the determination of a drug withdrawal period is one of the costly developmental procedures in drug development for food animals; thus it is believed that in the early developmental phases, a thorough pharmacokinetic characterization of a drug in the target species would greatly facilitate the design and quality of studies conducted in the later phases of new drug development. It is suggested that drugs that are intended for use in food animals can be characterized kinetically in less costly studies, the results of which might be used to determine the feasibility of developing a drug that might cause serious residue problems. It is also suggested that the pharmacokinetic modeling of a drug in the target animal may provide an essential data base for calculating dosage rates and intervals that directly relate to the efficacy aspects of drug development.

show abstract

Dosage Formulation

Lyubimov¹

2010

Pharmaceutical Sciences Encyclopedia

View full text Add to dashboard Cite

Drug formulation aims to determine experimentally all the variables necessary to develop an optimal formula and working directions for making the pharmaceutical product. Pharmaceutical technology applied to developing a drug formulation comprises selection of materials and procedures that are adaptable to various processes that lend themselves to inclusion in specific dosage forms. This article focuses on new dosage formulations, their function and characterization, absorption mechanisms, and novel routes of delivery.

show abstract

Tissue damage and concentration at the injection site after intramuscular injection of chemotherapeutics and vehicles in pigs

Cited by 45 publications

References 4 publications

Tissue damage at the injection site after intramuscular injection of drugs in hens

Tissue damage at the injection site after intramuscular injection of drugs in hens

Application of pharmacokinetic methods to the drug residue profile

Dosage Formulation

Contact Info

Product

Resources

About