Tips and tricks to improve sentinel lymph node mapping with Indocyanin green in endometrial cancer

Body, Noémie; Grégoire, Jean; Renaud, Marie-Claude; Sebastianelli, Alexandra; Grondin, Katherine; Plante, Marie

doi:10.1016/j.ygyno.2018.06.001

Cited by 36 publications

(27 citation statements)

References 24 publications

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“…In our experience, the robotic platform provides a stable, highly magnified three‐dimensional view of the operative field and the scaled motion of robotic equipment allowed for precise dissection, minimizing bleeding, making following the finely blue stained lymphatic channels to the nodes easier than during laparotomy or laparoscopy and potentially improve the mapping success rate. In addition, swollen blue lymphatic channels are not easily be mistakenly identified as a sentinel node as has been reported with ICG dyes potentially minimizing false positive identification of the SLN . The use of ICG dyes has been reported to lead to 7% to 8% falsely positive identified SLN (specimen without nodal tissues identified) after final pathologic processing .…”

Section: Discussionmentioning

confidence: 96%

“…In addition, swollen blue lymphatic channels are not easily be mistakenly identified as a sentinel node as has been reported with ICG dyes potentially minimizing false positive identification of the SLN. 28 The use of ICG dyes has been reported to lead to 7% to 8% falsely positive identified SLN (specimen without nodal tissues identified) after final pathologic processing. 29 where the SLN cohort had improved pelvic sidewall relapse free survival compared with those undergoing full complete nodal dissections (HR 0.32; 95% CI, 0.14-0.74; P = .007).…”

Section: Discussionmentioning

confidence: 99%

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Robotic sentinel node mapping in clinical stage 1 endometrial cancer using methylene blue dyes using the robotic platform

McDonald

Samant

et al. 2019

Robotics Computer Surgery

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Purpose Endometrial cancer is a surgically staged cancer. We examined our preliminary experience with sentinel lymph node (SLN) mapping in early stage endometrial cancer using methylene blue dyes. Method Retrospective review of all clinically stage 1 endometrial cancer staged surgically using the robotic platform. Logistic regression models were built to predict nodal metastasis taking into account age, grade, histology, depth of myometrial invasion, cervical involvement, and use of SLN mapping. Results Four hundred sixty‐nine patients were reviewed. Sixty patients had SLN mapping (13%). Four hundred nine patients underwent standard lymphadenectomy with five documented nodal metastasis (1.2%). Five nodal metastasis (8.3%) were seen in the SLN patients. In the logistic model, the application of SLN mapping was significantly associated with diagnosed nodal metastasis (OR 7.74; 95% CI, 2.04‐29.3; P = .003) together with nonendometroid histology (OR 5.05; 95% CI, 1.27‐20.12; P = .022). Conclusion SLN mapping protocol using methylene blue significantly identifies more nodal metastasis than standard lymphadenectomy.

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Robotic sentinel node mapping in clinical stage 1 endometrial cancer using methylene blue dyes using the robotic platform

McDonald

Samant

et al. 2019

Robotics Computer Surgery

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“…A retrospective analysis of patients who underwent primary surgery for EC with SLN mapping using ICG, followed by pelvic lymphadenectomy, was conducted by Body et al ., to determine the validity of SLN mapping with ICG in EC. [27] Body et al . found that ICG is an excellent tracer for SLN mapping in EC, while advanced FIGO stage associated with failed bilateral detection ( P = 0.01).…”

Section: Methods Of Sentinel Lymph Node Detection In Endometrial Cancersmentioning

confidence: 99%

“…found that ICG is an excellent tracer for SLN mapping in EC, while advanced FIGO stage associated with failed bilateral detection ( P = 0.01). [27]…”

Section: Methods Of Sentinel Lymph Node Detection In Endometrial Cancersmentioning

confidence: 99%

Sentinel lymph nodes in endometrial cancer update 2018

Abdelazim

Abu-Faza²,

Zhurabekova

et al. 2019

Gynecol Minim Invasive Ther

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There are no established data about lymphadenectomy during treatment of endometrial cancers (ECs) and to what extent lymphadenectomy should be performed. In addition, retroperitoneal lymphadenectomy increases the intraoperative and postoperative complications. Sentinel lymph node (SLN) mapping has the lowest costs and highest quality-adjusted survival. SLN is the most cost-effective strategy in the management of low-risk ECs. Women staged with SLN mapping were more likely to receive adjuvant treatment compared with women staged with systemic lymphadenectomy. This review article designed to evaluate the diagnostic accuracy and the methods of SLN detection in ECs.

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“…J. Alex и D. Krag и D. Krag и соавт. [8][9][10][11] внедрили в клиническую практику интраоперационный портативный гамма-сканер. Для этого используют коллоид, меченый технецием 99m, который используется в виде следующих препаратов: 99mTC-SC, 99mTC-HCA, 99mTC-HAS [12][13][14].…”

Section: Introductionunclassified

Current Techniques for Detecting Sentinel Lymph Nodes in Vulvar Cancer

Ганцев

Lipatov

Menshikov

2019

Kreativnaâ hirurgiâ i onkologiâ

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Введение. Рак вульвы относится к группе редких новообразований и составляет около 4 % от всех гинекологических злокачественных опухолей. Одним из важных барьеров в распространении опухолевой клеточной популяции являются лимфатические узлы. Большинство онкологов признает факт существования так называемых сторожевых лимфатических узлов. Адекватная оценка состояния этого узла позволяет прогнозировать масштабы распространения рака, что, в свою очередь, обеспечивает результат хирургического лечения. Материалы и методы. На базе отделения онкогинекологии РКОД за период с 2015 по 2018 год получили хирургическое лечение 87 пациенток со злокачественными новообразованиями вульвы. У 19 пациенток с верифицированным раком вульвы произведена вульвэктомия с использованием детекции сторожевого лимфатического узла. Использовались методы контрастной лимфографии и непрямой интраоперационной радиоизотопной лимфосцинтиграфии. Отмечалось минимальное количество послеоперационных осложнений. Результаты. Основываясь на верификации сторожевого лимфоузла, оптимизировали объем хирургического лечения рака вульвы. Заключение. Детекция сторожевых лимфатических узлов при раке вульвы является эффективным методом планирования объема хирургического лечения, что, в свою очередь, снижает количество послеоперационных осложнений. Снижение количества послеоперационных осложнений благоприятно сказывается на качестве жизни пациенток.

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Tips and tricks to improve sentinel lymph node mapping with Indocyanin green in endometrial cancer

Cited by 36 publications

References 24 publications

Robotic sentinel node mapping in clinical stage 1 endometrial cancer using methylene blue dyes using the robotic platform

Robotic sentinel node mapping in clinical stage 1 endometrial cancer using methylene blue dyes using the robotic platform

Sentinel lymph nodes in endometrial cancer update 2018

Current Techniques for Detecting Sentinel Lymph Nodes in Vulvar Cancer

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