Tips-17 a First-in-Human Feasibility Study to Evaluate the Safety of Selective Intra-Arterial Yttrium-90 Microsphere Treatment in Patients With Recurrent Glioblastoma (The Frontier Trial)
Abstract:BACKGROUND: Glioblastoma (GBM) is the most aggressive primary brain tumor that virtually always recurs with no established standard therapy at recurrence. Median survival after recurrence is 7-12 months. Selective internal radiation therapy (SIRT) with Yttrium-90 (Y90) glass microspheres (TheraSphere™, Boston Scientific, Marlborough, MA) is an FDA approved standard treatment for hepatocellular carcinoma, and represents a novel strategy to treat regionally localized brain tumors. We are conducting a first-in-hu… Show more
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