“…The dihydro-2-pyrones isolated from microbial sources have shown a diverse range of biological activities. Some of their activities include anticancer, anti-HIV, antifungal, neurotoxic, cytotoxic, phytotoxic, and activities (Dickinson, 1993, Thaisrivongs et al, 1996Poppe et al, 1997;Turner et al, 1998). The mechanism of anticancer activity of 2-pyrones involves inhibition of DNA synthesis in the cells (Trachootham et al, 2008).…”