Tip 2 diyabet hastalarında dolaşımdaki B-tipi natriüretik peptidin osteoporoz ile ilişkisi

Abstract

Objective: The aim of this study was to evaluate the relationship of circulating B-type natriuretic peptide (BNP) with osteoporosis in type 2 diabetes mellitus (T2DM) patients.
 Material and Method: 95 patients with T2DM were included in the study. Patients with circulating BNP levels in their patient file systems and whose BMD were measured within 15 days were included in the study. The patients were divided into three groups according to their BMD scores as normal, osteopenia and osteoporosis. The relationship between circulating BNP and diabetic osteoporosis and other parameters was investigated.
 Results: A total of 95 patients, 75 female and 20 male, were included in our study. The mean age of the patients was 66.09±5.96 years. Gender, age and BMI were similar between the groups. The duration of DM was found to be significantly higher in the osteoporosis group (p

The relationship between serum pro-B type natriuretic peptide level and bone mineral density in peritoneal dialysis patients

“…In studies conducted in T2DM patients, a negative correlation was found between circulating BNP and BMD. [ 26 ] In our study, we found that increased serum NT-pro-BNP levels were associated with decreased lumbar T-scores, and serum levels of NT-pro-BNP were an important and independent predictor of lumbar BMD in PD patients.…”