Tiotropium could provide benefits in the early stage of COPD, but further studies are needed

Pharmacology and Therapeutics of Bronchodilators Revisited

“…However, it has not yet been determined whether early intervention with a long-acting bronchodilator modifies the long-term course of COPD. Therefore, much larger and longer studies are needed to address this challenge (Cazzola and Rogliani, 2018).…”