Tinnitus perception in patients after vagal nerve stimulator implantation for epilepsy

Wichova, Helena; Alvi, Sameer; Shew, Matthew; Lin, James; Sale, Keith A.; Larsen, Christopher G.; Staecker, Hinrich

doi:10.1016/j.amjoto.2018.07.009

Cited by 6 publications

(1 citation statement)

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“…However, in addition to the absence of a control group, the short treatment duration (4-min session at each location for 2 weeks) was different from other tVNS protocols, which performed treatment for several hours each day for several weeks (Table 3). Wichova et al (2018) retrospectively evaluated epilepsy patients with tinnitus who received VNS as a treatment for their epilepsy. Phone inquiries regarding changes in the loudness of tinnitus (VAS) showed that 16 of 20 patients had at least one quieter moment.…”

Section: Clinical Studies On (T)vns Alone In Tinnitus Patientsmentioning

confidence: 99%

Direct and Transcutaneous Vagus Nerve Stimulation for Treatment of Tinnitus: A Scoping Review

Yakunina

Nam

2021

Front. Neurosci.

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Recent animal research has shown that vagus nerve stimulation (VNS) paired with sound stimuli can induce neural plasticity in the auditory cortex in a controlled manner. VNS paired with tones excluding the tinnitus frequency eliminated physiological and behavioral characteristics of tinnitus in noise-exposed rats. Several clinical trials followed and explored the effectiveness of VNS paired with sound stimuli for alleviating tinnitus in human subjects. Transcutaneous VNS (tVNS) has received increasing attention as a non-invasive alternative approach to tinnitus treatment. Several studies have also explored tVNS alone (not paired with sound stimuli) as a potential therapy for tinnitus. In this review, we discuss existing knowledge about direct and tVNS in terms of applicability, safety, and effectiveness in diminishing tinnitus symptoms in human subjects. This review includes all existing clinical and neuroimaging studies of tVNS alone or paired with acoustic stimulation in tinnitus patients and outlines the present limitations that must be overcome to maximize the potential of (t)VNS as a therapy for tinnitus.

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Section: Clinical Studies On (T)vns Alone In Tinnitus Patientsmentioning

confidence: 99%