J. Neurosci. Res. volume 86, issue 11, P2564-2578 2008 DOI: 10.1002/jnr.21699 View full text
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Carol A. Bauer, Jeremy G. Turner, Donald M. Caspary, Kristin S. Myers, Thomas J. Brozoski

Abstract: A long-standing hypothesis is that tinnitus, the perception of sound without an external acoustic source, is triggered by a distinctive pattern of cochlear hair cell (HC) damage and this subsequently leads to altered neural activity in the central auditory pathway. This hypothesis was tested by assessing behavioral evidence of tinnitus and spontaneous neural activity in the inferior colliculus (IC) after unilateral cochlear trauma. Chinchillas were assigned to 4 cochlear treatment groups. Each treatment produ…

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