Timing of ventriculoatrial shunt removal on renal function recovery of patients with shunt nephritis: Case report and systematic review

Ajlan, Balgees A.; Maghrabi, Yazid; Almukhtar, Ghadeer; Baeesa, Saleh

doi:10.1016/j.clineuro.2022.107279

Cited by 7 publications

(3 citation statements)

References 25 publications

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“…Arterial stenosis and vascular blockage of the transplanted kidney lead to decreased blood perfusion of the transplanted kidney, resulting in a series of pathophysiological changes and renal tissue damage, which is generally mainly acute tubular injury. Such patients have a higher probability of DGF after surgery [13] . In this study, after comparing the above related risk factors among the three groups of patients, it was shown that there was no significant difference in DGF risk factors and clinical data comparison among the three groups, which ensured the rigor and credibility of the following study.…”

Section: Resultsmentioning

confidence: 97%

Combined Efficacy of Diosmin and Ulinastatin on Renal Injury Markers and Ultrasound Indicators in Delayed Renal Function Recovery

Yuan¹,

Qi²,

Meng³

2023

IJPS

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Renal transplantation, as an effective treatment for end-stage renal disease, has many clinical complications, among which delayed graft function recovery, as one of the common postoperative complications, is also a major risk factor affecting the short-term and long-term efficacy of renal transplantation. Therefore, reasonable use of delayed graft function after renal transplantation to promote renal function recovery is of great significance for the prognosis of these patients. Based on this, 62 patients who underwent renal transplantation and developed delayed graft function in our hospital from June 2017 to December 2019 were selected as the research objects. According to the random color method, they were divided into three groups; diosmin group (n=20), ulinastatin group (n=21) and combination group (n=21). To observe the effects of different medication regimens on renal injury markers and renal ultrasound related indexes in patients with delayed graft function and to lay a theoretical foundation for guiding clinical medication and improving prognosis of delayed graft function recovery patients. After comparing the general data of the three groups, it was found that there was no significant difference (p>0.05), indicating that there was no difference in medication results due to personal factors. The levels of serum creatinine, cystatin and blood urea nitrogen in the ulinastatin group after treatment were significantly better than those before treatment. The levels of renal injury markers in the combined group were significantly better after treatment than before treatment. According to the ultrasound results, there was no significant difference in the renal ultrasound indexes between the diosmin and ulinastatin groups after treatment, while the renal ultrasound indexes of the combined group were better than those of the other two groups. It can be concluded from the results that diosmin combined with ulinastatin can significantly reduce renal injury in patients with delayed graft function and can effectively improve renal function in such patients, which has a positive effect on improving prognosis.

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Section: Resultsmentioning

confidence: 97%

Combined Efficacy of Diosmin and Ulinastatin on Renal Injury Markers and Ultrasound Indicators in Delayed Renal Function Recovery

Yuan¹,

Qi²,

Meng³

2023

IJPS

View full text Add to dashboard Cite

show abstract

“…Arterial stenosis and vascular blockage of the transplanted kidney lead to decreased blood perfusion of the transplanted kidney, resulting in a series of pathophysiological changes and renal tissue damage, which is generally mainly acute tubular injury. Such patients have a higher probability of DGF after surgery [13] . In this study, after comparing the above related risk factors among the three groups of patients, it was shown that there was no signi cant difference in DGF risk factors and clinical data comparison among the three groups, which ensured the rigor and credibility of the following study.…”

Section: Related Workmentioning

confidence: 97%

Effect of diosimin combined with ulinastatin on renal injury markers and renal ultrasound indicators in patients with delayed renal function recovery after transplantation

Yuan

Meng

2022

Preprint

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Backgroud: Renal transplantation, as an effective treatment for end-stage renal disease, has many clinical complications, among which delayed graft function recovery (DGF), as one of the common postoperative complications, is also a major risk factor affecting the short-term and long-term efficacy of renal transplantation. Therefore, reasonable use of DGF after renal transplantation to promote renal function recovery is of great significance for the prognosis of these patients. Methods: Based on this, 62 patients who underwent renal transplantation and developed DGF in our hospital from June 2018 to December 2021 were selected as the research objects. According to the random color method, they were divided into three groups: diosimin group (n=20), ulinastatin group (n=21), and combination group (n=21). To observe the effects of different medication regimens on renal injury markers and renal ultrasound related indexes in patients with DGF, and to lay a theoretical foundation for guiding clinical medication and improving prognosis of DGF patients. Results: After comparing the general data of the three groups, it was found that there was no significant difference (P > 0.05), indicating that there was no difference in medication results due to personal factors. The levels of Scr, CysC and BUN in the ulinastatin group after treatment were significantly better than those before treatment. The levels of renal injury markers in the combined group were significantly better after treatment than before treatment. According to the ultrasound results, there was no significant difference in the renal ultrasound indexes between the diosimine and ulinastatin groups after treatment, while the renal ultrasound indexes of the combined group were better than those of the other two groups. Conclusion: It can be concluded from the results that diosimin combined with ulinastatin can significantly reduce renal injury in patients with DGF, and can effectively improve renal function in such patients, which has a positive effect on improving prognosis.

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“…Diabetes is the primary cause of chronic kidney disease [CKD], with the majority of diabetic nephropathy [DN] patients finally requiring renal replacement therapy [1] . Diabetic nephropathy is one of the commonest diabetic microvascular complications accounting for 20-40% of diabetic patients [2,3] .…”

Section: Introductionmentioning

confidence: 99%

Assessment of Autotaxin, Oxidized LDL and β2-Microglobulin in Patients with Diabetic Nephropathy

Farid,

Mahmoud,

Madanay

et al. 2023

International Journal of Medical Arts

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Article information Background: Diabetes mellitus [DM] is a metabolic condition characterized by hyperglycemia caused by deficiencies in insulin action or secretion or both. Diabetes' persistent hyperglycemia is linked to long-term organ failure, including kidney loss of functions, leading to diabetic nephropathy [DN]. Aim of the work: This study aims to assess the value of serum autotaxin [ATX], oxidized LDL [ox LDL], and β2microglobulin [β2M] as biomarkers for DN patients. Patients and Methods: This cross-sectional study included 100 subjects divided into three groups. Group 1; control group [20 healthy subjects]. Patients were subdivided into two groups, group 2 [40 patients diagnosed with DN stages Ⅰ, Ⅱ, and Ⅲ], and group 3 which involved 40 patients diagnosed with DN stages Ⅳ and Ⅴ.Results: As regards the ATX, it was significantly higher in group 3 than in group 1 and group 2 with a statistically significant difference between every 2 groups [P value > 0.05 for all]. In terms of Ox LDL and β2M, the difference between the three groups was significant statistically [P value = 0.005, and 0.002 respectively], however the difference between group 2 and group 3 was not significant [P value = 0.44, and 0.98 respectively]. Conclusion:Serum autotaxin, ox LDL, and β2M can be used as diagnostic noninvasive biomarkers in DN.

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Timing of ventriculoatrial shunt removal on renal function recovery of patients with shunt nephritis: Case report and systematic review

Cited by 7 publications

References 25 publications

Combined Efficacy of Diosmin and Ulinastatin on Renal Injury Markers and Ultrasound Indicators in Delayed Renal Function Recovery

Combined Efficacy of Diosmin and Ulinastatin on Renal Injury Markers and Ultrasound Indicators in Delayed Renal Function Recovery

Effect of diosimin combined with ulinastatin on renal injury markers and renal ultrasound indicators in patients with delayed renal function recovery after transplantation

Assessment of Autotaxin, Oxidized LDL and β2-Microglobulin in Patients with Diabetic Nephropathy

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