Timing of revascularization in patients with transient ST-segment elevation myocardial infarction: a randomized clinical trial

Lemkes, Jorrit S.; Janssens, Gladys N.; Hoeven, Nina W. van der; Ven, Peter M. van de; Marques, Koen M.; Leeuwen, Maarten A.H. van; Appelman, Yolande; Knaapen, Paul; Verouden, Niels; Allaart, Cornelis P.; Brinckman, Stijn L.; Saraber, Colette E; Plomp, Koos; Timmer, Jorik R.; Kedhi, Elvin; Hermanides, Renicus S; Meuwissen, Martijn; Schaap, Jeroen; Weerdt, Arno P. van der; Rossum, Albert C. van; Nijveldt, Robin; Royen, Niels van

doi:10.1093/eurheartj/ehy651

Cited by 42 publications

(22 citation statements)

References 18 publications

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“…This new recommendation is based on the results of the COACT trial enrolling 552 patients and showing no difference in 90‐day survival between immediate and delayed coronary angiography 11 . A 24‐hour time window to perform coronary angiography is now recommended for patients with transient ST‐segment elevation on ECG based on the relatively good prognosis of these patients and the results of a randomized trial involving 142 patients showing no benefit in terms of infarct size at magnetic resonance imaging between patients who underwent immediate (within a median 0.3 hours) vs delayed (within a median of 23 hours) coronary angiography 12 …”

Section: Invasive Strategymentioning

confidence: 99%

What is new in the 2020 ESC NSTE‐ACS guidelines

Roffi

2021

Eur J Clin Investigation

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Section: Invasive Strategymentioning

confidence: 99%

What is new in the 2020 ESC NSTE‐ACS guidelines

Roffi

2021

Eur J Clin Investigation

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“…Patients with transient STEMI appear to have a more favorable prognosis than patients with persistent STEMI. Previous studies demonstrated a smaller infarct size in transient STEMI and the recently published randomized TRANSIENT trial found similar outcomes for an immediate, STEMI-like, and a delayed, NSTEMIlike, invasive approach [4][5][6] . Spontaneous early reperfusion in transient STEMI is most likely the cause of the limited infarct size.…”

Section: Introductionmentioning

confidence: 77%

“…For the current study we included patients from two prospective multicentre studies, the TRANSIENT trial (n=142) and the REDUCE-MVI trial (n=110). The study design and main results of both studies have been published previously 6,[8][9][10] . Both study protocols conform to the Declaration of Helsinki and ethics approval was obtained by the respective institutional review boards (local medical ethics committees).…”

Section: Study Participantsmentioning

confidence: 99%

Transient ST-elevation myocardial infarction versus persistent ST-elevation myocardial infarction. An appraisal of patient characteristics and functional outcome

Janssens

Lemkes

Hoeven

et al. 2021

International Journal of Cardiology

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This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

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“…Transiente ST-Streckenhebungen (weniger als 20 min) waren in Beobachtungsstudien mit einer guten Prognose assoziiert. Passend dazu profitierten Patienten mit einer transienten ST-Streckenhebung in der TRANSIENT-Studie nicht von einer umgehenden im Vergleich zu einer späteren Koronarangiografie (empfohlenes 24-h-Zeitfenster) [19,20,21].…”

Section: Glossarunclassified

Risikostratifizierung des NSTE-ACS

Hartung

Jobs

Thiele

2021

Aktuelle Kardiologie

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ZusammenfassungMit zunehmender Verbesserung der Prognose der NSTE-ACS-Patientenkollektive in den letzten Jahren spielt eine standardisierte, schnelle und gute diskriminierende Risikostratifizierung eine erhebliche Rolle. Verschiedene Merkmale des langfristig erwartbaren ischämischen Risikos, wie z.B. klinische Parameter, EKG-Indikatoren, Biomarker und klinische Scores, werden zusammen mit dem individuellen Blutungsrisiko erfasst und integriert. So ist z.B. die absolute Höhe der Troponin-Konzentration prädiktiv für die Gesamtletalität. Der GRACE-Risk-Score wird nicht nur zusätzlich zur objektiven Risikostratifizierung empfohlen, sondern ein Punktwert >140 ist eines der Kriterien für eine frühe Koronarangiografie innerhalb von 24 Stunden. Die Abschätzung des Blutungsrisikos entsprechend der ARC-HBR-Kriterien hat einen Einfluss auf das antithrombotische Therapieregime.

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Timing of revascularization in patients with transient ST-segment elevation myocardial infarction: a randomized clinical trial

Cited by 42 publications

References 18 publications

What is new in the 2020 ESC NSTE‐ACS guidelines

What is new in the 2020 ESC NSTE‐ACS guidelines

Transient ST-elevation myocardial infarction versus persistent ST-elevation myocardial infarction. An appraisal of patient characteristics and functional outcome

Risikostratifizierung des NSTE-ACS

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