Timing of Ossification in Duck, Quail, and Zebra Finch: lntraspecific Variation, Heterochronies, and Life History Evolution

Mitgutsch, Christian; Wimmer, Corinne; Sánchez‐Villagra, Marcelo R.; Hahnloser, Richard H. R.; Schneider, Richard A.

doi:10.2108/zsj.28.491

Cited by 59 publications

(100 citation statements)

References 84 publications

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“…The first evidence of any mineralization was observed in the distal tibia of quail and duck at HH33 (data not shown), but there was no Alizarin red staining anywhere in the head skeleton of quail or duck (Figure 2A and data not shown), which is consistent with previous observations in chick and other avian species (Mitgutsch et al, 2011; Pechak et al, 1986). The bones of the craniofacial skeleton of quail and duck showed their first signs of mineralization at HH34 (Fig 2C, D).…”

Section: Resultssupporting

confidence: 90%

Evolution of a developmental mechanism: Species-specific regulation of the cell cycle and the timing of events during craniofacial osteogenesis

Hall

Jheon

Ealba

et al. 2014

Developmental Biology

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109

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Neural crest mesenchyme (NCM) controls species-specific pattern in the craniofacial skeleton but how this cell population accomplishes such a complex task remains unclear. To elucidate mechanisms through which NCM directs skeletal development and evolution, we made chimeras from quail and duck embryos, which differ markedly in their craniofacial morphology and maturation rates. We show that quail NCM, when transplanted into duck, maintains its faster timetable for development and autonomously executes molecular and cellular programs for the induction, differentiation, and mineralization of bone, including premature expression of osteogenic genes such as Runx2 and Col1a1. In contrast, the duck host systemic environment appears to be relatively permissive and supports osteogenesis independently by providing circulating minerals and a vascular network. Further experiments reveal that NCM establishes the timing of osteogenesis by regulating cell cycle progression in a stage- and species-specific manner. Altering the time-course of D-type cyclin expression mimics chimeras by accelerating expression of Runx2 and Col1a1. We also discover higher endogenous expression of Runx2 in quail coincident with their smaller craniofacial skeletons, and by prematurely over-expressing Runx2 in chick embryos we reduce the overall size of the craniofacial skeleton. Thus, our work suggests that NCM establishes species-specific size in the craniofacial skeleton by controlling cell cycle, Runx2 expression, and the timing of key events during osteogenesis.

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Section: Resultssupporting

confidence: 90%

Evolution of a developmental mechanism: Species-specific regulation of the cell cycle and the timing of events during craniofacial osteogenesis

Hall

Jheon

Ealba

et al. 2014

Developmental Biology

Self Cite

109

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“…Three-dimensional rendering and visualization were performed using DRISHTI v. 1.0 (Drishti Paint and Render, [23]). Following the protocol of Mitgusch et al [24], observed ossified elements were tabulated for each specimen (electronic supplementary material, S1). Following Weisbecker [25], we distinguished clearly ossified bones ('B') from elements displaying barely detectable ossification ('m').…”

Section: (A) Data Collectionmentioning

confidence: 99%

Skeletal development in the African elephant and ossification timing in placental mammals

Hautier

Stansfield²,

Allen

et al. 2012

Proc. R. Soc. B.

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We provide here unique data on elephant skeletal ontogeny. We focus on the sequence of cranial and postcranial ossification events during growth in the African elephant (Loxodonta africana). Previous analyses on ossification sequences in mammals have focused on monotremes, marsupials, boreoeutherian and xenarthran placentals. Here, we add data on ossification sequences in an afrotherian. We use two different methods to quantify sequence heterochrony: the sequence method and event-paring/Parsimov. Compared with other placentals, elephants show late ossifications of the basicranium, manual and pedal phalanges, and early ossifications of the ischium and metacarpals. Moreover, ossification in elephants starts very early and progresses rapidly. Specifically, the elephant exhibits the same percentage of bones showing an ossification centre at the end of the first third of its gestation period as the mouse and hamster have close to birth. Elephants show a number of features of their ossification patterns that differ from those of other placental mammals. The pattern of the initiation of the ossification evident in the African elephant underscores a possible correlation between the timing of ossification onset and gestation time throughout mammals.

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“…During the last decade, advances in analytical methods now allow for explicit phylogenetic analyses of heterochrony sequences involving many types of events (cellular, molecular, genetic, and morphological) (Bininda‐Emonds et al ; Smith ). Ossification sequences of birds are little known, even when the information they provide could be useful in the determination of homologies, phylogenetic relationships, identification of taxa, or heterochronies (Feduccia and Nowicki ; Maisano ,; Maxwell ,,; Maxwell and Larsson ; Mitgutsch et al ). In addition, ossification in fossil embryos enables identification of morphological patterns in extinct groups (Organ et al ).…”

Section: Introductionmentioning

confidence: 99%

Skeletogenesis of Myiopsitta monachus (Psittaciformes) and sequence heterochronies in Aves

Carril

Tambussi

2016

Evolution and Development

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The ossification sequence of Myiopsitta monachus was determined. Myiopsitta has a similar sequence to other altricial birds, with delayed skeletons compared to precocial species. The hindlimbs ossify before the forelimbs, a condition that could be linked to altriciality. To determine the stability of the sequences of ossification across birds, we selected species of different groups of Aves and used event-pairing method and character mapping on a phylogeny. Our results show that the homogeneity in the development of birds was supported by 56.77% of the character states. Event-pair cracking phylogenetic method was applied to identify sequence heterochronies. Results reveal a high number of heterochronies and show that the long bones in limbs may behave as modules. In Myiopsitta, the ossa ectethmoidale and mesethmoidale ossify early. These bones provide the origin site of the Psittaciformes' novel adductor m. ethmomandibularis, associated with strong bite forces, and its acceleration in the sequence may correspond to the functional hypothesis. Also, the early appearance of some hyoid apparatus elements occurs, and could be related to the development of tongue in Psittaciformes and its role in handling food, and is in concordance with the functional and size hypothesis.

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Timing of Ossification in Duck, Quail, and Zebra Finch: lntraspecific Variation, Heterochronies, and Life History Evolution

Cited by 59 publications

References 84 publications

Evolution of a developmental mechanism: Species-specific regulation of the cell cycle and the timing of events during craniofacial osteogenesis

Evolution of a developmental mechanism: Species-specific regulation of the cell cycle and the timing of events during craniofacial osteogenesis

Skeletal development in the African elephant and ossification timing in placental mammals

Skeletogenesis of Myiopsitta monachus (Psittaciformes) and sequence heterochronies in Aves

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