Timing matters: Long term effects of adversities from prenatal period up to adolescence on adolescents’ cortisol stress response. The TRAILS study

Bosch, Nienke M.; Riese, Harriëtte; Reijneveld, Sijmen A.; Bakker, Martin P.; Verhulst, Frank C.; Ormel, Johan; Oldehinkel, Albertine J.

doi:10.1016/j.psyneuen.2012.01.013

Cited by 150 publications

(157 citation statements)

References 41 publications

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“…The brain develops rapidly in childhood, and research from both animal and human models suggests that when an area of the brain is rapidly developing, that region is more sensitive to environmental threats (4,5,(17)(18)(19). Most studies examining the effects of multiple adverse experiences and developmental outcomes have disregarded the effect of timing of exposure (9,20). Studies are often cross-sectional or assess adverse exposures over a broad developmental period (e.g., before 18 y of age).…”

Section: Introductionmentioning

confidence: 99%

Multiple adverse experiences and child cognitive development

2015

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Section: Introductionmentioning

confidence: 99%

Multiple adverse experiences and child cognitive development

2015

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“…Non-responders did not differ from responders in terms of sex; non-responders were slightly older (mean age 16.4 versus 16.1 year) [23].…”

Section: Study Participantsmentioning

confidence: 72%

Basal or stress-induced cortisol and asthma development: the TRAILS study

et al. 2012

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We examined the association between: 1) cortisol levels and asthma or asthma development; 2) cortisol levels upon stress and asthma. In addition, we performed a post hoc meta-analysis on results from the literature.Cortisol, cortisol upon stress, asthma (doctor diagnosis of asthma and/or symptoms and/or treatment in the past 12 months) and asthma development (asthma at a specific survey while not having asthma at the previous survey(s)) were assessed in the TRAILS study (n52230, mean age at survey 1 11 years, survey 2 14 years and survey 3 16 years). Logistic regression models were used to study associations between: 1) cortisol (cortisol awakening response, area under the curve (AUC) with respect to the ground (AUCg) or with respect to the increase (AUCi), and evening cortisol) and asthma or asthma development; 2) cortisol upon stress (AUCg or AUCi) and asthma. The meta-analyses included nine case-control articles on basal cortisol in asthma.No significant association was found between: 1) cortisol and asthma (age 11 years) or asthma development (age 14 or 16 years); 2) cortisol upon stress and asthma (age 16 years). The metaanalysis found lower morning and evening cortisol levels in asthmatics compared to nonasthmatics; however, the summary estimates were not significant.We found no evidence supporting a role for cortisol in asthma and asthma development.

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“…This research also showed that childhood adversity was associated with neuroticism in adulthood. This was explained by the influence child adversity has on the emotional reactivity in brain functioning (Bosch, Riese, Reijneveld, Bakker, Verhulst, Ormel, & Oldehinkel, 2012).…”

Section: Introductionmentioning

confidence: 99%

“…When exposed to incidents of interpersonal violence, the expectation is that certain primary personality factors will reflect changes, particularly those primary factors that are highly sensitive to environmental experience which has an impact on the hypothalamic-pituitary-adrenal (HPA) axis. The HPA axis and sympathetic-adrenal-medullary system are critical in promoting adaptive responses to stress, anxiety or fear, thus contributing to the regulation of the stress response (Bosch et al, 2012;De Kloet, Vermetten, Gouze, Kavelaars, Heijnen, & Westenberg, 2006).…”

Section: Introductionmentioning

confidence: 99%

The expression of personality among adolescents exposed to community interpersonal violence

Visser

Coetzee

Claassen

2015

South African Journal of Psychology

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The high level of crime in South Africa affects many adolescents. Experience of community interpersonal violence affects the social, emotional and cognitive functioning of adolescents and could have an impact on their personality development. The aim of the study was to explore possible differences in the expression of personality between adolescents exposed to community interpersonal violence and those not exposed to such violence. The sample comprised 183 grade 12 learners from a secondary school in a middle class community in Gauteng. Participants were divided into two groups: adolescents who reported exposure to community interpersonal violence (n = 93) and those who did not report exposure to such violence (n = 90). Both groups completed the 16 Personality Factor and Posttraumatic Diagnostic Scales. Differences between the groups were explored using a one-way betweengroups multivariate analysis of variance (MANOVA) and t-tests for independent groups.Results indicated statistically significant differences between the two groups on Factor G 1 (rule consciousness), Factor I (emotional sensitivity) and Factor Q4 (anxiety). Adolescents exposed to interpersonal violence reported higher levels of posttraumatic stress disorder (PTSD) symptoms than the control group. The group that experienced PTSD symptoms differed more in terms of personality functioning (Factor I and Q4). Violence-exposed adolescents experienced more emotional volatility, difficulty to regulate emotions, anxiety and sensitivity to environmental stressors than those not exposed to such violence. Although causality cannot be assumed, it is possible that exposure to community interpersonal violence, which could result in PTSD symptoms, has implications for the personality development of adolescents. Interventions for adolescents exposed to interpersonal violence are recommended to prevent the development of PTSD symptoms.

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Timing matters: Long term effects of adversities from prenatal period up to adolescence on adolescents’ cortisol stress response. The TRAILS study

Cited by 150 publications

References 41 publications

Multiple adverse experiences and child cognitive development

Multiple adverse experiences and child cognitive development

Basal or stress-induced cortisol and asthma development: the TRAILS study

The expression of personality among adolescents exposed to community interpersonal violence

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