Timing, approach, and treatment strategies for infected pancreatic necrosis: a narrative review

Abstract

ancreatic necrosis occurs in approximately 15% to 20% of patients with acute pancreatitis (AP); 1/3 of patients are diagnosed with infected pancreatic necrosis (IPN), which has a mortality rate of 30%. It is the chief reason for the second "death peak" of AP patients in the later stage of the disease. [1] As one of the most vital treatment methods for IPN, pancreatic necrosectomy has developed rapidly in the past 30 years, including improvements and breakthroughs in surgical timing, approach, and strategies, and a significant reduction in postoperative mortality from the initial 30% to 40%. In particular, with the innovation of laparoscopic and endoscopic techniques, pancreatic surgeons have more choices in the face of IPN. Currently, how to optimize treatment and maximize the benefits for IPN patients has become a topic of great concern and controversy in the treatment of IPN.Data sharing not applicable to this article as no datasets were generated or analyzed during the current study.