Timing and evolution of periventricular haemorrhage in infants weighing 1250 g or less at birth.

Szymonowicz, W.; Yu, V. Y. H.

doi:10.1136/adc.59.1.7

Cited by 41 publications

(10 citation statements)

References 22 publications

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“…This accounted for the finding that growth retardation was associated with increased survival in this and another study. 7 The fact that perinatal asphyxia was associated with increased mortality emphasised the importance of prevention or early detection and treatment of asphyxia in the management of extremely preterm labour.…”

Section: Discussionmentioning

confidence: 99%

Perinatal factors and adverse outcome in extremely low birthweight infants.

Yu¹,

Downe²,

Astbury³

et al. 1986

Archives of Disease in Childhood

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SUMMARY Perinatal factors associated with death or disability at 2 years were identified in an inborn cohort of 196 live births with a birth weight of 500-999 g. Antepartum haemorrhage, multiple pregnancy, breech presentation, perinatal asphyxia, hypothermia on admission, hyaline membrane disease, persistent pulmonary hypertension, severe respiratory failure, and intraventricular haemorrhage were associated with increased mortality. Factors associated with increased survival included maternal hypertension, caesarean birth, increasing maturity or size at birth, female sex, and fetal growth retardation. Stepwise multiple discriminant function analysis showed that six factors correctly classified the outcome in 83% of infants: intraventricular haemorrhage was the most important factor followed by the presence of acidosis and hypoxia in the early neonatal period, birth weight, pre-eclamptic toxaemia, and caesarean birth. This study also showed that intraventricular haemorrhage, seizures, antepartum haemorrhage and delay in regaining birth weight were associated with increased disability among survivors.

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Section: Discussionmentioning

confidence: 99%

Perinatal factors and adverse outcome in extremely low birthweight infants.

Yu¹,

Downe²,

Astbury³

et al. 1986

Archives of Disease in Childhood

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“…Details of perinatal care (Obeyesekere et a!. 1980;Yu 1977;Yu et al 19796, 1981, 19826;Wilson et al 1983) and neonatal complications Yu & Hollingsworth 1979;Yu et al 1979aYu et al , 1982aYu et al , 1983Szymonowicz & Yu 1984) in these infants at QVMC have been reported previously.…”

Section: Methodsmentioning

confidence: 74%

“…The percentage of outborn infants in these published series ranged from 17% to 100% making meaningless any comparison between hospitals because of the profound selection bias that can operate in the transport process (Kitchen et al 1983(Kitchen et al , 1984aSaigal et al 1984). Furthermore, the percentage of small-for-gestational age (SGA) infants ranged from 7% to 51% again suggesting differences in the gestational age of these weight-selected populations, a factor which is known to influence outcome significantly (Yu et al 1984~).…”

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confidence: 99%

Outcome of extremely‐low‐birthweight infants

Yu¹,

Wong²,

Bajuk³

et al. 1986

BJOG

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Summary. The overall 1‐year survival rate of 261 infants born at 500 g–999 g over a 7‐year period was 46%. The survival rate of the 220 inborn infants, corrected for birth defects, would have increased from 47% to 57% if delivery room deaths were excluded and to 62% if postneonatal deaths had also been ignored. Survival improved progressively with increasing 100 g weight groups. The disability rate in the 108 survivors who were at least 2 years old corrected for prematurity was 28% with little variation between the 100 g weight groups. There were no significant trends in annual perinatal mortality, 1‐year survival and disability rate in survivors over the study period for the inborn population. The male infants had significantly lower normal‐survival rate than the female infants. Small‐for‐gestational‐age infants, comprising 11% of the inborn group, had significantly better survival but a higher disability rate. Multiple births had significantly lower survival and normal‐survival rates than had singleton births. Infants whose mothers were transferred for delivery at the perinatal centre before onset of labour had a significantly better survival rate than those whose mothers had ‘booked’ and those who were transferred in labour.

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“…In view of current interest to establish the predictive value of perinatal risk factors associated with PIVH, it is of interest to note that previous studies using real-time ultrasound scanning report maximal efficiency for diagnosis of PIVH on day 14 [16,20]. Significant intraventricular hemorrhage may be missed by ultrasound, particularly if ultrasound scan is obtained within few days of the time of hemorrhage since fresh blood may initially appear sonolucent [5].…”

Section: Discussionmentioning

confidence: 99%