Timed Sequence Task: A New Paradigm to Study Motor Learning and Flexibility in Mice
Anna Urushadze,
Milan Janicek,
Alice Abbondanza
et al.
Abstract:Motor learning and flexibility allow animals to perform routine actions efficiently while keeping them flexible. A number of paradigms are used to test cognitive flexibility, but not many of them focus specifically on the learning of complex motor sequences and their flexibility. While many tests use operant or touchscreen boxes that offer high throughput and reproducibility, the motor actions themselves are mostly simple presses of a designated lever. To focus more on motor actions during the operant task and… Show more
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