Time Trends in Unilateral and Bilateral Oophorectomy in a Geographically Defined American Population

Erickson, Zachary K.; Rocca, Walter A.; Smith, Carin Y.; Rocca, Liliana Gazzuola; Stewart, Elizabeth A.; Laughlin-Tommaso, Shannon K.; Mielke, Michelle M.

doi:10.1097/aog.0000000000004728

Cited by 13 publications

(12 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…23 Although the baseline cohort could be affected by higher rates of prior hysterectomy or unilateral salpingo-oophorectomy among patients in racial and ethnic minority groups, compared with non-Hispanic White patients, the overall rate of these procedures in the ages selected for this study is low. 39–41 Furthermore, although differences in ovarian histology by race or ethnicity could explain our findings, 42,43 race and ethnicity remained significant predictors of fertility-sparing procedures after controlling for histology. Lastly, incidental diagnoses of cancer at the time of surgery, although not different by race or ethnicity, accounted for the majority of cases for cervical and ovarian cancer in our study, which could affect interpretation of our findings.…”

Section: Discussionmentioning

confidence: 57%

Disparities in Fertility-Sparing Treatment and Use of Assisted Reproductive Technology After a Diagnosis of Cervical, Ovarian, or Endometrial Cancer

Jorgensen

Meernik

et al. 2023

Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

To assess the presence of sociodemographic and clinical disparities in fertility-sparing treatment and assisted reproductive technology (ART) use among patients with a history of cervical, endometrial, or ovarian cancer. METHODS:We conducted a population-based cohort study of patients aged 18-45 years who were diagnosed with cervical cancer (stage IA, IB), endometrial cancer (grade 1, stage IA, IB), or ovarian cancer (stage IA, IC) between January 1, 2000, and December 31, 2015, using linked data from the CCR (California Cancer Registry), the California Office of Statewide Health Planning and Development, and the Society for Assisted Reproductive Technology. The primary outcome was receipt of fertilitysparing treatment, defined as surgical or medical treatment to preserve the uterus and at least one ovary. The secondary outcome was fertility preservation, defined as ART use after cancer diagnosis. Multivariable logistic regression analysis was used to estimate odds ratios and 95% CIs for the association between fertilitysparing treatment and exposures of interest: age at diagnosis, race and ethnicity, health insurance, socioeconomic status, rurality, and parity. RESULTS:We identified 7,736 patients who were diagnosed with cervical, endometrial, or ovarian cancer with eligible histology. There were 850 (18.8%) fertilitysparing procedures among 4,521 cases of cervical cancer, 108 (7.2%) among 1,504 cases of endometrial cancer, and 741 (43.3%) among 1,711 cases of ovarian cancer. Analyses demonstrated nonuniform patterns of sociodemographic disparities by cancer type for fertilitysparing treatment, and ART. Fertility-sparing treatment was more likely among young patients, overall, and of those in racial and ethnic minority groups among

show abstract

Section: Discussionmentioning

confidence: 57%

Disparities in Fertility-Sparing Treatment and Use of Assisted Reproductive Technology After a Diagnosis of Cervical, Ovarian, or Endometrial Cancer

Jorgensen

Meernik

et al. 2023

Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

show abstract

“…Given these and other reports 27 that highlighted the health risks of premenopausal BSO in women at average risk for ovarian cancer, Rocca and colleagues recently assessed trends in the occurrence of unilateral oophorectomy or BSO versus ovarian conservation among all women residing in the Minnesota county (Olmsted) in which Mayo Clinic is located, and who underwent gynecologic surgery between 1950 and 2018. 28 The investigators limited their analysis to women who had undergone unilateral oophorectomy or BSO between ages 18 and 49 years (these women are assumed to have been premenopausal). The authors considered as indications for oophorectomy primary or metastatic ovarian cancer, risk-reducing BSO for women at elevated risk for ovarian cancer (for example, strong family history or known BRCA gene mutation), adnexal mass, endometriosis, torsion, and other benign gynecologic conditions that included pelvic pain, abscess, oophoritis, or ectopic pregnancy.…”

Section: Oophorectomy Trends Trackedmentioning

confidence: 99%

“…We agree with the authors' speculation that beginning with Parker's 2005 publication, 23 ObGyns have become more conservative in performing unindicated BSO in women at average risk for ovarian cancer, now recognizing that the harms of this procedure often outweigh any benefits. 28 Women with BRCA1 and BRCA2 gene mutations are at elevated risk for ovarian, tubal, and breast malignancies. In this population, risk-reducing BSO dramatically lowers future risk of ovarian and tubal cancer.…”

Section: Oophorectomy Trends Trackedmentioning

confidence: 99%

2022 Update on menopause

Kaunitz¹

2022

OBGM

View full text Add to dashboard Cite

“…O parkinsonismo é uma síndrome clínica com maior incidência nos homens do que nas mulheres, o qual se caracteriza por bradicinesia, rigidez, tremor de descanso e Brazilian Journal of Development, Curitiba, v.9, n.2, p. 7890-7904, feb., 2023 instabilidade postural, tendo como principal causa a doença de Parkinson (DP) idiopática BLÜMEL et al, 2022;ULDBIERG et al, 2022;ERICKSON et al, 2022;GEORGAKIS;PETRIDOU, 2021;IBRAHIM et al, 2022).…”

Section: Introductionunclassified

Associação entre a ooforectomia bilateral precoce e o desenvolvimento do parkinsonismo e Doença de Parkinson em mulheres na pré-menopausa

Ázar¹,

Correia²,

Souza³

et al. 2023

Braz. J. Develop.

View full text Add to dashboard Cite

O parkinsonismo é um distúrbio do sistema nervoso de maior incidência masculina do que feminina, visto que, por mecanismos fisiológicos, o estrogênio possui efeitos neuroprotetores, com funções como aumento da dopamina, um neurotransmissor essencial para o controle das funções motoras. Além disso, previne a formação dos corpúsculos de Lewy e da agregação da α-sinucleína, responsáveis pela progressão da Doença de Parkinson. Por isso, a doença se apresenta diferentemente nas mulheres. A remoção cirúrgica de ambos os ovários em mulheres na pré-menopausa para a prevenção do câncer de ovário parece favorecer o surgimento da doença, tendo em vista a perda da produção do hormônio protetor. Assim, o objetivo do estudo é analisar a associação entre a ooforectomia bilateral precoce e o desenvolvimento de parkinsonismo e Doença de Parkinson em mulheres na pré-menopausa. Trata-se de uma revisão bibliográfica sistemática, do tipo quantitativa, que utilizou as plataformas do PubMed, SciELO e Cochrane Library como bases de dados para seleção dos artigos, todos na língua inglesa. Foram utilizadas literaturas publicadas com recorte temporal de 2017 a 2022. De acordo com as literaturas analisadas, a ooforectomia bilateral precoce em mulheres na pré-menopausa aumenta o risco do desenvolvimento de parkinsonismo. Desse modo, a diminuição dos procedimentos cirúrgicos profiláticos para câncer de ovário nas pacientes com risco médio de malignidade reduziria o risco dessa condição.

show abstract

Time Trends in Unilateral and Bilateral Oophorectomy in a Geographically Defined American Population

Abstract: The incidence of premenopausal unilateral and bilateral oophorectomy has steadily decreased in the past 14 years, likely due to increased recognition of the long-term harmful sequelae.

Cited by 13 publications

References 41 publications

Disparities in Fertility-Sparing Treatment and Use of Assisted Reproductive Technology After a Diagnosis of Cervical, Ovarian, or Endometrial Cancer

Disparities in Fertility-Sparing Treatment and Use of Assisted Reproductive Technology After a Diagnosis of Cervical, Ovarian, or Endometrial Cancer

2022 Update on menopause

Associação entre a ooforectomia bilateral precoce e o desenvolvimento do parkinsonismo e Doença de Parkinson em mulheres na pré-menopausa

Contact Info

Product

Resources

About