Time‐tracking of the research profile of a drug using bibliometric tools

Bordons, María; Bravo, Carmen; Barrigón, Santos

doi:10.1002/asi.10397

Cited by 17 publications

(16 citation statements)

References 23 publications

(20 reference statements)

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“…What could also be another limitation of this study is the restriction of the 3‐year period of interest, preventing a longitudinal analysis. Looking at the literature, only a single publication exploring the usefulness of bibliometric analyses to detect trends of research profiles of another therapeutic drug, aspirin, was found [23]. Several differences between this study and the present study ( Medline vs. SCI database, several decade vs. a 3‐year period of interest, utilization of Medical Subject Headings Index vs. simple word search track, etc.…”

Section: Discussionmentioning

confidence: 66%

Quantitative analysis of the scientific literature on acetaminophen in medicine and biology: a 2003–2005 study†

Robert¹,

Saenz-Feijoo

Gaudy³

et al. 2009

Fundamemntal Clinical Pharma

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This study quantifies the utilization of acetaminophen in life sciences and clinical medicine using bibliometric indicators. A total of 1626 documents involving acetaminophen published by 74 countries during 2003-2005 in the Thompson-Scientific Life sciences and Clinical Medicine collections were identified and analyzed. The USA leads in the number of publications followed by the UK, and industrialized countries, including France, Japan and Germany; the presence of countries such as China, India and Turkey among the top 15 countries deserves to be noticed. The European Union stands as a comparable contributor to the USA, both in terms of number of publications and in terms of profile of papers distributed among subcategories of Life Sciences and Clinical Medicine disciplines. All documents were published in 539 different journals. The most prolific journals were related to pharmacology and/or pharmaceutics. All aspects of acetaminophen (chemistry, pharmacokinetics, metabolism, etc.) were studied with primary interest for therapeutic use (42%) and adverse effects (28%) comprising a large part of publications focusing on acetaminophen hepatotoxicity. This quantitative overview provides as to the interest of the scientific community in this analgesic and completes the various review documents that regularly appear in the scientific literature.

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Section: Discussionmentioning

confidence: 66%

Quantitative analysis of the scientific literature on acetaminophen in medicine and biology: a 2003–2005 study†

Robert¹,

Saenz-Feijoo

Gaudy³

et al. 2009

Fundamemntal Clinical Pharma

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“…It was followed by Sweden, with 9.6 articles, and USA with 5.0 papers per million people. The country with the highest number of published articles recorded in PubMed in all fields of science per million inhabitants was Sweden (13,355 articles), followed by Denmark, with 10,689 articles and Switzerland (10,416). South Korea was the country with the highest Activity Index on dioxins (0.73%), followed by Finland (0.20%) and Czech Republic, USA and UK (0.08%) ( Table 3).…”

Section: Resultsmentioning

confidence: 98%

“…Journals were sorted decreasingly according to the number of published articles. To assess the main concerns of researchers on dioxins we also studied the subheadings or qualifiers for the major term Tetrachlorodibenzodioxin that MeSH includes 10 (Table 1) and time trend of the most frequently used subheadings was plotted. Bradford zones and Bradford constant were calculated, and a Bradford-Zipf plot was made.…”

Section: Methodsmentioning

confidence: 99%

Scientific production on tetrachloro-dibenzo-dioxins: A bibliometric study

2006

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Tetrachloro-dibenzo-dioxins were declared as human carcinogenic substances in 1997. Objective: to analyse the scientific production about tetrachloro-dibenzo-dioxins between 1976 and 2005.Solla Price and Bradford models were applied. Different aspects of papers were analysed. Impact factor of journals was studied.3484 articles were found. The number of articles published each year is fitted to Solla Price model.It has been shown the scientific literature dispersion. Specialisation of some journals of Nucleus and 1 st Bradford Zone has been shown.

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“…Bordons et al (2004) demonstrated the usefulness of bibliometric analyses to detect trends in the research of a therapeutic drug including the evolution of drug studies over time. The most interesting in relation to the TJSI is the study by Koenig (1982) who dealt with the relationship between the success rate of drugs and different factors of research performance.…”

Section: Discussionmentioning

confidence: 99%

Top Journals Selectivity Index: is it acceptable for drugs beyond the field of analgesia?

Kissin

Bradley

2011

Scientometrics

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To predict the success of an analgesic drug we have suggested a bibliometric indicator, the Top Journals Selectivity Index (TJSI) (Kissin, Scientometrics, 86:785-795, 2011). It represents the ratio (as %) between the number of all types of articles on a particular drug in the top 20 biomedical journals and the number of articles on that drug in all ([5,000) journals covered by Medline over the first 5 years after a drug's introduction. For example, the highest TJSI score among analgesics was that of sumatriptan, the most successful drug for the treatment of migraine. The aim of this study was to demonstrate that TJSI may be used not only in the field of analgesics, but also for various other categories of drugs. The study tested two hypotheses. First, the difference between the most successful and less successful drugs in any pharmacological class can be reliably detected by TJSI. Second, drugs with TJSI indicators as high as that of sumatriptan can be found among other pharmacological classes as well. Drugs from various pharmacological classes approved by the Federal Drug Administration (FDA) during the 10-year period, 1980-1989, were used in this study. Two groups of 10 drugs were selected to test the first hypothesis. One group included the most successful (breakthrough) drugs; the other included less successful drugs matched with the breakthrough drugs according to mechanism of action. The difference between the two groups was compared using three publication indices: the TJSI, the number of all types of articles on a drug in journals presented by Medline (AJI), and the number of articles covering only randomized controlled trials (RCT). It was found that TJSI can detect the difference between the two groups of drugs better than the two other indices. TJSI detected the difference between a breakthrough drug and its less successful counterpart at least 69% of the time with 95% confidence. With the other two indices the difference was not distinguishable from random chance.can be useful not only in the field of analgesics, but also with drugs belonging to other pharmacological classes.

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Time‐tracking of the research profile of a drug using bibliometric tools

Cited by 17 publications

References 23 publications

Quantitative analysis of the scientific literature on acetaminophen in medicine and biology: a 2003–2005 study†

Quantitative analysis of the scientific literature on acetaminophen in medicine and biology: a 2003–2005 study†

Scientific production on tetrachloro-dibenzo-dioxins: A bibliometric study

Top Journals Selectivity Index: is it acceptable for drugs beyond the field of analgesia?

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