Time to relapse following treatment for methamphetamine use: A long-term perspective on patterns and predictors

Brecht, Mary‐Lynn; Herbeck, Diane M.

doi:10.1016/j.drugalcdep.2014.02.702

Cited by 210 publications

(159 citation statements)

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“…Several studies examining drug-use severity, for example, have identified frequency of use at treatment entry to be an important factor that affects treatment response (Simpson et al, 2002;Vaillant, 1988). Recent studies with clinical samples of MAdependent users also support the importance of considering MA-severity when examining posttreatment outcomes, since heavy or daily use is considered to increase one's risk for relapse (Brecht and Herbeck, 2014;Elkashef et al, 2008Elkashef et al, , 2012Heinzerling et al, 2014).…”

Section: Discussionmentioning

confidence: 99%

“…Medication studies, for example, have demonstrated that MA-dependent participants with lower baseline levels of MA use tend to have better outcomes (fewer MA-positive urine samples than those with higher baseline MA use (Elkashef et al, 2008;Heinzerling et al, 2014;Shoptaw et al, 2008). Similarly, in longitudinal outcome studies of MAdependent users (Brecht and Herbeck, 2014), lower MA severity at treatment admission serves as a strong predictor of posttreatment abstinence. Findings from these studies suggest that current clinical trial outcome studies for MA-dependence should consider the differential efficacy of experimental treatment regimens by MA use severity at treatment admission.…”

Section: Introductionmentioning

confidence: 99%

“…Several studies have documented a high posttreatment rate of relapse among MA-dependent individuals, showing that the benefits of treatment quickly diminish within the postdischarge period, starting as early as 3 months (Brecht et al, 2005(Brecht et al, , 2008Brecht and Herbeck, 2014;Gonzales et al, 2010;Hser et al, 2003Hser et al, , 2005Rawson et al, 2002Rawson et al, , 2004Roll et al, 2006). Consequently, there is considerable interest in identifying interventions that can help reduce relapse to MA use, particularly among subgroups of MA-dependent users.…”

Section: Introductionmentioning

confidence: 99%

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Impact of an exercise intervention on methamphetamine use outcomes post residential treatment care

Rawson

Chudzynski

Gonzales-Castaneda

et al. 2015

Drug and Alcohol Dependence

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Background-We examined the efficacy of an 8-week exercise intervention on posttreatment methamphetamine (MA) use among MA-dependent individuals following residential treatment.Methods-135 individuals newly enrolled in treatment were randomly assigned to a structured 8-week exercise intervention or health education control group. Approximately 1 week after completion of the intervention, participants were discharged to the community. Interview data and urine samples were collected at 1-, 3-, and 6-months post-residential care. Of the sample, 54.8% were classified as higher severity users (using MA more than 18 days in the month before admission) and 45.2% as lower severity users (using MA for up to 18 days in the month before admission). Group differences in MA use outcomes were examined over the 3 timepoints using mixed-multivariate modeling.Results-While fewer exercise participants returned to MA use compared to education participants at 1-, 3-and 6-months post-discharge, differences were not statistically significant. A significant interaction for self-reported MA use and MA urine drug test results by condition and MA severity was found: lower severity users in the exercise group reported using MA significantly fewer days at the three post-discharge timepoints than lower severity users in the ContributorsAuthors RAR, LM, and CBC were involved with the design the study. Authors RG, JC, BAS managed literature searches and summaries of previous related work. Authors JP, DD, and BD undertook behavioral and clinical data collection. AA and RG undertook the statistical analysis. All authors contributed to the writing of the manuscript, including the review and final approval of it for publication. Conflicts of interest: none.Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. HHS Public Access Author Manuscript Author ManuscriptAuthor ManuscriptAuthor Manuscript education group. Lower severity users in the exercise group also had a lower percentage of positive urine results at the three timepoints than lower severity users in the education group. These relationships were not present in the comparison of the higher severity conditions. Conclusion-Resultssupport the value of exercise as a treatment component for individuals using MA 18 or fewer days/month.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Impact of an exercise intervention on methamphetamine use outcomes post residential treatment care

Rawson

Chudzynski

Gonzales-Castaneda

et al. 2015

Drug and Alcohol Dependence

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“…Since for methamphetamine a 1-year relapse rate of 61% and 10-year relapse rate of 77% (Brecht and Herbeck [12]) is reported, one could suggest that each year about 25 persons/100,000 inhabitants in this county may become dependent on methamphetamine.…”

Section: Discussionmentioning

confidence: 99%

Aspects of Methamphetamine Abuse in Adolescents and Young Adults in a Thuringian County

Dhein¹,

Schmelmer²,

Guenther³

et al. 2018

Eur Addict Res

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Background/Objective: Drug abuse is an increasing problem among young adults in European countries. We wanted to assess the prevalence of methamphetamine and cannabis use in young people and to ask for their socioeconomic, parental and emotional background. Methods: All pupils (n = 1,087) in the final class of 3 school types (general school [in Germany: Hauptschule/Regelschule mit Hauptschulabschluss] class 9, regular school [in Germany: Regelschule] class 10, high school [in Germany: Gymnasium] class 10) and the first 2 classes of the vocational school (in Germany: Berufsschule) in the entire rural district of Altenburger Land, a Thuringian county in Germany with a total of 92,344 inhabitants were asked to fill out a 2-page questionnaire. In all, 920 questionnaires could be finally evaluated (mean age: 16.6 ± 0.07 years; mode value: 16; maximum range: 13–29). Results: In the entire group, 5.81% (33 females, 20 males) reported the use of methamphetamine, while 42.8% stated that they have used it only once, the remaining 57.2% specified that they have used it on a more regular basis, mostly once a month, but 14.2% had used it almost daily. With regard to the socioeconomic background, 55% of the parents of the methamphetamine users were employees and 10% of the parents were in a leading position. This was not different from the non-user group (p = 0.193). Unemployment of the parents was found in 6.5% of the methamphetamine users and in 4.7% of the non-users. Overall, 67.92% had a basic knowledge of the side effects of this drug. In 55.32% of the methamphetamine users, the parents lived alone, were divorced or widowed, while this was only 33.1% in the non-user group. Of all the methamphetamine users, 69% had friends who also consumed the drug, which may give a hint on the impact of a peer group. In the entire group, 29.84% were smokers (female group: 28.47%; male group 31.25%) and 25.5% consumed cannabis. Ecstasy was used by a total of 4.05% and cocaine by 1.53%. No participant mentioned that they have used opiates. Conclusion: Among pupils aged about 16 years nearly 6% reported to have consumed methamphetamine. This group has a middle socioeconomic background. Two factors were strongly associated with methamphetamine usage: a family with only a single parent and friends who were used to taking methamphetamine. The self-perception of users was generally considered to be a disadvantage as compared to the other factors.

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“…Il est important de noter que cette étude excluait les personnes ayant des antécédents psychiatriques, voire un diagnostic actuel d'un trouble mental. Parmi les prédicteurs d'un taux de rechute plus faible au sein de personnes avec abus de MA cinq années après la fin de leur traitement, Brecht et Herbeck (2014) soulignent qu'avoir vécu des séquelles mentales importantes liées à la MA (ex. : psychose ou dépression), avoir participé à plus de sessions de traitement et avoir continué à rechercher du soutien ou des traitements à la fin du programme offert pré-disait une plus longue abstinence.…”

Section: Traitementunclassified

La méthamphétamine – un stimulant comme les autres ou un problème plus complexe ?

Lecomte

Massé

2014

smq

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La méthamphétamine (MA) fait beaucoup couler d’encre dans les médias, par sa popularité grandissante ainsi que par ses effets psychotropes et néfastes. S’agit-il d’un stimulant comme un autre, ou la méthamphétamine entraîne-t-elle des difficultés spécifiques chez ses utilisateurs ? Cet article se veut une brève revue de la documentation scientifique décrivant les raisons de sa popularité ainsi que les problèmes physiques, dentaires, psychiatriques, cognitifs et judiciaires qui y sont associés. Les profils d’utilisateurs ainsi que les traitements proposés à ce jour seront également présentés. En somme, nous tenterons d’illustrer la complexité des troubles rencontrés chez l’utilisateur de MA, les similitudes avec les utilisateurs de stimulants, ainsi que les limites des traitements actuels pour répondre aux besoins liés à cette complexité.Methamphetamine (MA) has recently become very popular in the media, due in part to its increasing popularity as well as its psychotropic effects and the negative consequences of its use. Is it a stimulant like any other, or does methamphetamine use lead to specific difficulties in its users? The aim of this article is to provide a brief review of the literature by explaining some of the reasons for its popularity in Canada as well as the physical, dental, psychiatric, cognitive and legal problems associated with its use. MA’s popularity: Regarding its popularity, MA has benefitted from multiple factors, namely its low cost for users and manufacturers, its quick and intense psychotropic effects (increased energy, sexual arousal, rapid thinking, sleeplessness, lack of appetite), its easy access, as well as its various methods of ingestion (nasal, oral, injection). MA abuse also results in a multitude of negative effects, both physical and mental. MA’s physical effects: In terms of negative physical effects, cardiac problems, skin infections, sexually transmitted (and injection-related) diseases as well as meth mouth are described. MA’s mental effects: In terms of mental consequences, two recently published Canadian studies revealing high rates of depression symptoms and of sustained psychotic symptoms in a subgroup of MA users are presented. Studies reporting various cognitive deficits in MA user are also reviewed, including reports of high prevalence of childhood attention deficit and hyperactivity disorder diagnoses among adult MA users. Furthermore, MA abusers are documented as having been highly exposed to trauma in their lives, with many presenting with post-traumatic stress disorder criteria. This manuscript also explores the reasons behind the forensic profiles of individuals using MA, particularly the increased tendency toward violent acts, the high incarceration rates of the homeless users and the high percentage of individuals diagnosed with antisocial personality disorder reported in studies. In terms of user profiles, various methods of ingestion, frequency of use as well as combination with other drugs are described, with a special focus on the frequent polysubstance ab...

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Time to relapse following treatment for methamphetamine use: A long-term perspective on patterns and predictors

Cited by 210 publications

References 76 publications

Impact of an exercise intervention on methamphetamine use outcomes post residential treatment care

Impact of an exercise intervention on methamphetamine use outcomes post residential treatment care

Aspects of Methamphetamine Abuse in Adolescents and Young Adults in a Thuringian County

La méthamphétamine – un stimulant comme les autres ou un problème plus complexe ?

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