Time to Incurable Recurrence for Patients Treated With Pulmonary Metastasectomy for Colorectal Cancer

Matsuguma, Haruhisa; Mun, Mingyon; Yoshino, Ichiro; Hashimoto, Hiroshi; Shintani, Yasushi; Iida, Tomohiko; Shiono, Satoshi; Chida, Masayuki; Kuroda, Hiroaki; Nakayama, Mitsuo; Shiraishi, Yuji; Funai, Kazuhito; Kawamura, Masafumi

doi:10.1245/s10434-022-11904-7

Cited by 3 publications

(3 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Given that there are cases of cured patients such as case 2 in the present report, pneumonectomy should be considered if technically and physically feasible. If lung metastases reappear after pneumonectomy, an additional pneumonectomy may also lead to a favourable prognosis (19).…”

Section: Discussionmentioning

confidence: 99%

Stage IV and recurrent colorectal cancer cured following multimodal therapy: A case series

Kurata,

Imai,

Hirata

et al. 2024

Oncol Lett

View full text Add to dashboard Cite

The treatment strategies for colorectal cancer (CRC) with distant metastasis or metastatic recurrence after resection of the primary tumor are controversial. In the present study, four cases of patients with advanced CRC with distant metastasis who achieved disease-free survival (DFS) for >5 years and were deemed potentially cured were reported. Case 1 was that of a 53-year-old male patient with rectal cancer and liver metastases (pT3N2bM1, pStage IV), and case 2 was that of a 58-year-old female patient with descending colon cancer (pT3N1M1, pStage IV) who had lung metastases at surgery and postoperatively. Both patients achieved DFS for >5 years after simultaneous or staged partial hepatectomy or pneumonectomy followed by chemotherapy. Case 3 was that of a 75-year-old male patient with transverse colon cancer (pT3N1M0, pStage IIIB) and case 4 was that of a 73-year-old male patient with sigmoid colon cancer (pT3N0M0, pStage IIA). These cases developed liver metastases after resection of the primary tumour and were subsequently treated with chemotherapy before or after partial hepatectomy. DFS for >5 years was achieved. All four patients were considered cured. The data revealed that even patients with CRC and distant metastases can potentially be cured following multidisciplinary treatment. In the present case report, the factors that enabled these patients to be considered cured were discussed and the aim was to improve the treatment strategy to cure CRC with distant metastasis or recurrence.

show abstract

Section: Discussionmentioning

confidence: 99%

Stage IV and recurrent colorectal cancer cured following multimodal therapy: A case series

Kurata,

Imai,

Hirata

et al. 2024

Oncol Lett

View full text Add to dashboard Cite

show abstract

“…The better the effect of systemic treatment, the longer the interval between primary cancer and metastatic cancer, and the better the patient's general condition with supportive care, the better the effect of surgery will be. Giving these various considerations, the study of Matsugama et al 3 describes ''time to incurable recurrence'' as an outcome measure that can supplement current metrics regarding patient survivorship in the treatment of metastatic cancer.…”

Section: Other Factors That Affect Prognosis and Choice Of Treatmentmentioning

confidence: 99%

“…Matsuguma et al 3 provided support for surgery as a treatment for pulmonary metastatic cancer. The authors observed favorable 7-year overall survival for patients who underwent surgery after initial metastasectomy.…”

mentioning

confidence: 99%

Factors to Consider in Surgical Resection of Pulmonary Metastatic Carcinoma

Chen

2023

Ann Surg Oncol

View full text Add to dashboard Cite

ASO Author Reflections: New Indicator to Demonstrate Cure Probability: Time to Incurable Recurrence

et al. 2022

View full text Add to dashboard Cite

Time to Incurable Recurrence for Patients Treated With Pulmonary Metastasectomy for Colorectal Cancer

Cited by 3 publications

References 17 publications

Stage IV and recurrent colorectal cancer cured following multimodal therapy: A case series

Stage IV and recurrent colorectal cancer cured following multimodal therapy: A case series

Factors to Consider in Surgical Resection of Pulmonary Metastatic Carcinoma

ASO Author Reflections: New Indicator to Demonstrate Cure Probability: Time to Incurable Recurrence

Contact Info

Product

Resources

About