Time‐Resolved Fluorescence Techniques

Entangled Photon Correlations Allow a Continuous-Wave Laser Diode to Measure Single-Photon, Time-Resolved Fluorescence

“…19 These integrated pulsed lasers typically have a narrow wavelength tuning range, which can make measurements of multiple fluorescent probes or dynamics from multiple local environments difficult. 20 An intriguing alternative to pulsed lasers is to leverage the inherent quantum correlations between entangled photons in a pair. When one high-energy pump photon splits into a pair of two lower-energy entangled photons through spontaneous parametric down-conversion (SPDC), the two single photons are deterministically correlated in time.…”

“…To date, on-chip pulses are mostly in the picosecond range, although recent publications have shown pulses as short as 350 fs . These integrated pulsed lasers typically have a narrow wavelength tuning range, which can make measurements of multiple fluorescent probes or dynamics from multiple local environments difficult …”