Time Domain NMR in Polymer Science: From the Laboratory to the Industry

Besghini, Denise; Mauri, Michele; Simonutti, Roberto

doi:10.3390/app9091801

Cited by 84 publications

(68 citation statements)

References 118 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To ensure correct quantification of NMR signals, the longitudinal relaxation time (T 1 ) is one of the most important values . Relaxation describes the process of dynamic return of the spins to the initial equilibrium state after a pulse experiment and T 1 is the time that this process takes . It should be noted that individual T 1 ‐times are not substance constants, but dependent on experimental conditions i. e. solvent, magnetic field strength, temperature etc.…”

Section: Resultsmentioning

confidence: 99%

Benchtop NMR for Online Reaction Monitoring of the Biocatalytic Synthesis of Aromatic Amino Alcohols

2020

View full text Add to dashboard Cite

Online analytics provides insights into the progress of an ongoing reaction without the need for extensive sampling and offline analysis. In this study, we investigated benchtop NMR as an online reaction monitoring tool for complex enzyme cascade reactions. Online NMR was used to monitor a two‐step cascade beginning with an aromatic aldehyde and leading to an aromatic amino alcohol as the final product, applying two different enzymes and a variety of co‐substrates and intermediates. Benchtop NMR enabled the concentration of the reaction components to be detected in buffered systems in the single‐digit mM range without using deuterated solvent. The concentrations determined via NMR were correlated with offline samples analyzed via uHPLC and displayed a good correlation between the two methods. In summary, benchtop NMR proved to be a sensitive, selective and reliable method for online reaction monitoring in (multi‐step) biosynthesis. In future, online analytic systems such as the benchtop NMR devices described might not only enable direct monitoring of the reaction, but may also form the basis for self‐regulation in biocatalytic reactions.

show abstract

Section: Resultsmentioning

confidence: 99%

Benchtop NMR for Online Reaction Monitoring of the Biocatalytic Synthesis of Aromatic Amino Alcohols

2020

View full text Add to dashboard Cite

show abstract

“…It can thus be seen that the NMR FID, T 2 * and true T 2 may give information on the sample that for different applications is variously characterised as mobility, dynamics, stiffness, viscosity or rigidity. These are highly useful parameters, rapidly providing data on the physical state of the sample as a function of local condition and sample temperature [1][2][3].…”

Section: Nuclear Magnetic Resonance Relaxation (Nmrr) For Materials Scmentioning

confidence: 99%

“…NMR Relaxation (NMRR) is an extremely useful quantitative technique for material science, particularly for studying polymers and porous materials [1][2][3][4][5][6][7][8][9][10][11][12][13] Some applications of the Lab-Tools Peltier thermo-electrically cooled variable-temperature (V-T) probe [28,29] are also discussed, Section 2.1, which enables this spectrometer to make NMRC measurements of pore-size distributions in porous materials on the unusually wide pore scale range of sub 1 nm to over one micron [18]. Specific application examples are discussed in detail, Section 5.…”

Section: Introductionmentioning

confidence: 99%

Some Applications of a Field Programmable Gate Array Based Time-Domain Spectrometer for NMR Relaxation and NMR Cryoporometry

Webber¹

2020

Applied Sciences

View full text Add to dashboard Cite

Featured Application: This compact but precision highly stable NMR time-domain relaxation spectrometer is most useful for quantitative material science measurements of both the mass and the mobility/dynamics/stiffness/viscosity/rigidity of hydrocarbons and polymers, both in the bulk and in sub-nano-meter and upward sized pores. It is highly useful for studying the properties of hydrocarbons in pores in applications such as recovered porous rock samples from oil reservoirs, and in fired biochar porous carbon samples, to give just two examples. In addition, applicable to both these fields of study is the ability to make NMR Cryoporometric measurements of pore-size distributions in porous materials, for sub-nano-to over micrometer sized pores.Abstract: NMR Relaxation (NMRR) is an extremely useful quantitative technique for material science, particularly for studying polymers and porous materials. NMR Cryoporometry (NMRC) is a powerful technique for the measurement of pore-size distributions and total porosities. This paper discusses the use, capabilities and application of a newly available compact NMR time-domain relaxation spectrometer, the Lab-Tools Mk3 NMR Relaxometer & Cryoporometer [Lab-Tools (nano-science), Ramsgate, Kent, UK (2019)]. Being Field Programmable Gate Array based means that it is unusually compact, which makes it particularly suitable for the lab bench-top, in the field and also mobile use. Its use with a variable-temperature NMR probe such as the Lab-Tools Peltier thermo-electrically cooled variable-temperature (V-T) probe is also discussed. This enables the NMRC measurement of pore-size distributions in porous materials, from sub-nano-to over 1 micron sized pores. These techniques are suitable for a wide range of porous materials and also polymers. This instrument comes with a Graphical User Interface (GUI) for control, which also enables both online and offline analysis of the measured data. This makes it is easy to use for material science studies both in the field and in university, research institute, company and even school laboratories. The Peltier cooling gives the precision temperature control and smoothness needed by NMR Cryoporometry, particularly near the probe liquid bulk melting point. Results from example NMR Relaxation and NMR Cryoporometric measurements are given.

show abstract

“…NMR relaxation is widely used for studying various polymers and polymer systems (Besghini et al 2019), such as polystyrene (Gasilova et al 1993), micellar and liquid crystalline systems (Wong 2006), polyhydroxyalkanoates (Nishida et al 2018), polyfluoroacryhlates (Borisova et al 1980) and especially tetrafunctional oligoetheracrilates (OEA) (Fig. 1).…”

Section: Nuclear Magnetic Relaxation Study: Oligoetheracrilatesmentioning

confidence: 99%

Relaxation methods for studying transformations in polymer systems

Levine

Iroh

Tallman

2020

Physics of Complex Systems

View full text Add to dashboard Cite

It is known that self-organisation of nanostructures according to the bottom-up approach is driven by the competition of several processes: surface tension, diffusion, gravity, buoyant force and, perhaps, molecular coordination phenomenon. The last one was discussed in the 70s in terms of the so-called "mobile organised molecular arrays" and proved with the help of nuclear magnetic relaxation. This study shows examples of self-organised structures obtained electrochemically by authors and provides a discussion regarding the same terms.

show abstract

Time Domain NMR in Polymer Science: From the Laboratory to the Industry

Cited by 84 publications

References 118 publications

Benchtop NMR for Online Reaction Monitoring of the Biocatalytic Synthesis of Aromatic Amino Alcohols

Benchtop NMR for Online Reaction Monitoring of the Biocatalytic Synthesis of Aromatic Amino Alcohols

Some Applications of a Field Programmable Gate Array Based Time-Domain Spectrometer for NMR Relaxation and NMR Cryoporometry

Relaxation methods for studying transformations in polymer systems

Contact Info

Product

Resources

About