Time-domain diffuse optical tomography using silicon photomultipliers: feasibility study

Abstract

Abstract. Silicon photomultipliers (SiPMs) have been very recently introduced as the most promising detectors in the field of diffuse optics, in particular due to the inherent low cost and large active area. We also demonstrate the suitability of SiPMs for time-domain diffuse optical tomography (DOT). The study is based on both simulations and experimental measurements. Results clearly show excellent performances in terms of spatial localization of an absorbing perturbation, thus opening the way to the use of SiPMs for DOT, with the possibility to conceive a new generation of low-cost and reliable multichannel tomographic systems. © The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.

In vivo Study of the Layered Structure on the Abdomen by Broadband Time-Domain Diffuse Optical Spectroscopy

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Time-Gated Single-Photon Detection in Time-Domain Diffuse Optics: A Review

“…Indeed, in the last years several clinical and diagnostics applications [8,131] adopted DOT due to its capability to improve the imaging of deep inhomogeneities of the medium (e.g., tumor, local changes in O 2 Hb/HHb due to brain activation, etc.). The technological improvements in terms of both detectors (matrix of small detectors or large area ones) and detection electronics allows one to have faster measurements, thus going in the direction of real-time tracking of buried objects [132][133][134][135]. Additionally, the use of multiple-view acquisitions coupled to the tomographic reconstruction enables: (i) to overcome the limitation in spatial resolution typical of the diffuse optics; (ii) to improve the quantification of the absorption and scattering coefficient of the inclusion [136][137][138].…”

In vivo depth heterogeneity of the abdomen assessed by broadband time-domain diffuse optical spectroscopy

“…Spectral tunability is achieved by dispersing the source with a Pellin-Broca prism and coupling the selected wavelength into an optical fiber. To achieve higher responsivity, two different detectors, a Silicon Photomultiplier (SiPM) [6,7] and Hamamatsu InGaAs PMT, are used to cover a wide spectral region. A pellicle beam splitter is used to change detector at desired wavelength.…”