Time-dependent reduction in load to failure of wedge-type polyglyconate suture anchors

Demirhan, Mehmet; Kılıçoğlu, Önder; Akpınar, Sercan; Akman, Şenol; Atalar, Ata Can; Goksan, M. Alp

doi:10.1016/s0749-8063(00)90083-5

Cited by 16 publications

(6 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In contrast to the adequacy of initial strengths of bioabsorbable implants, data about biodegradation rates indicate a possibility for a premature strength loss, especially for devices made of PGA [4]. An in vivo study found a wedge‐type PGA suture anchor to loose 75% of its initial pullout strength within the first 3 weeks [8]. There are a comparatively small number of studies concerning the degradation‐dependent changes in fixation strength of bioabsorbable interference screws.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Failure strength of bioabsorbable interference screws: effects of in vivo degradation for 12�weeks

Kılıçoğlu

Demirhan

Akman

et al. 2003

Knee Surgery, Sports Traumatology, Arthroscopy

Self Cite

View full text Add to dashboard Cite

We investigated the effect of in vivo degradation for 6-12 weeks on the fixation strength of polylactide bioabsorbable interference screws. Ten bioabsorbable interference screws were used to fix the patellar tendon autograft in ten live sheep knees, which were equally divided into two groups and killed in the 6th or 12th week. The control group consisted of four cadaveric knees. Following the killing of the animals the screws were retrieved and reused to fix patellar tendon grafts in cadaveric sheep knees. Tendon pull-out tests were performed for the partially degraded screws, for the control group, and for the reused screws of the control group. Macroscopic and microscopic examinations of the 6- and 12-week specimens were performed. Tendons pulled-out with an average force of 357+/-30 N in the cadaveric control group on the first use and with 465+/-118 N on the second use. The partially degraded screws failed with a mean load of 399+/-119 N in the 6-week group, and 12-week screws at 447+/-72 N. No macroscopic sign of degradation was observed on the retrieved screws. Histological examination of the 6 week specimens showed necrotic changes in the tendon around screw contact areas. Healing with granulation tissue was present in the same area in the 12th week. Foreign body reaction or an excessive inflammatory reaction was not observed. In vivo degradation of poly- l-lactide interference screws for 12 weeks thus causes neither a loss in the fixation strength of the screws nor an obvious inflammatory reaction.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The aim of this study was to investigate the probable time‐dependent changes in fixation strength expected in bioabsorbable screws. A bioabsorbable screw made of PLLA was chosen because the reported high degradation rates of the PGA materials [4, 8, 21]. The PLLA screw was expected to be retrievable even after biodegradation for 12 weeks.…”

Section: Discussionmentioning

confidence: 99%

Failure strength of bioabsorbable interference screws: effects of in vivo degradation for 12�weeks

Kılıçoğlu

Demirhan

Akman

et al. 2003

Knee Surgery, Sports Traumatology, Arthroscopy

Self Cite

View full text Add to dashboard Cite

show abstract

“…It is also unknown how long these absorbable implants need to retain their integrity and strength before the tissue heals adequately to the bone to resist stress. With a uniaxial load to failure in a sheep tibial model, Demirhan et al 25 examined the pullout strength of a biodegradable wedge-type suture anchor primarily made of PGA (TAG, Acufex Microsurgical). They found that the load to failure of this particular implant to pullout decreased by 75% of its initial pullout strength within 3 weeks, 84% in 6 weeks, and 85% in 12 weeks.…”

Section: Biology Of Soft Tissue Fixation Devicesmentioning

confidence: 99%

Suture Anchors and Tacks for Shoulder Surgery, Part 1

et al. 2005

View full text Add to dashboard Cite

The development and successful clinical application of suture anchors and tacks have revolutionized the surgeon's ability to secure soft tissues to bone via open or arthroscopic surgical techniques. When used carefully and with proper technique, these devices provide viable options for the repair and reconstruction of many intra-articular and extra-articular abnormalities in the shoulder, including rotator cuff tears, shoulder instability, and biceps lesions that require labrum repair or biceps tendon tenodesis. Like many technologies, however, the successful application of these devices requires an understanding of the biology and biomechanics that affect their use in the shoulder as well as knowledge of the factors that can affect subsequent clinical outcomes, including complications.

show abstract

“…In 2000 Demierhan et al assessed the clinical performance of the early biodegradable anchors with the Acufex PGA wedge (Acufex Microsurgical Inc.) compared to plastic version in an in vivo sheep model, demonstrating a significant drop in fixation strength of 84% with a decrease in pull out strength from 134 N to 23 N at 6 weeks (Demirhan et al, 2000). This was worrying as the time frame for rehabilitation intensification lies around this time point, however the current applicability of this evidence is questioned as this research was performed with one of the faster degrading polymers no longer in clinical use.…”

Section: Materials Choicementioning

confidence: 99%