Time-dependent bioactivity of preparations from cactus pear (Opuntia ficus indica) and ice plant (Mesembryanthemum crystallinum) on human skin fibroblasts and keratinocytes

Deters, Alexandra; Meyer, Ulrich; Stintzing, Florian C.

doi:10.1016/j.jep.2012.05.014

Cited by 22 publications

(15 citation statements)

References 19 publications

(27 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The plant was widely used in traditional medicine for the respiratory or urinary system and has been used as an antidiabetic agent in Japan [13,69,70,71]. The pressed juice of the plant influences the cell physiology of human keratinocytes and fibroblasts and improves skin hydration in atopic patients [72,73]. …”

Section: Discussionmentioning

confidence: 99%

Children with Dry Skin and Atopic Predisposition: Daily Use of Emollients in a Participant-Blinded, Randomized, Prospective Trial

Schario

Lünnemann²,

Stroux³

et al. 2014

Skin Pharmacol Physiol

View full text Add to dashboard Cite

Background: Dry skin reflects a skin barrier defect which can lead to atopic dermatitis. Little is known about the distinct effects of emollient use in children with dry skin and atopic predisposition. Objectives: We investigated the effects of daily application of pressed ice plant juice (PIPJ)-based emollients and petrolatum-based emollients. Methods: Children aged 2-6 years with dry skin and atopic predisposition were randomized into 2 groups: group 1 received emollients containing PIPJ and natural lipids, while group 2 received petrolatum-based emollients. Skin condition and biophysical properties of the skin barrier were assessed at inclusion and weeks 4, 12 and 16. Results: Skin condition improved significantly in all children. Comparing the groups, children treated with emollients containing PIPJ showed significantly higher stratum corneum hydration values and significantly lower transepidermal water loss values at week 16 on the forearm and forehead. A significant decrease in skin pH was noted in group 2 on the forearm and forehead; group 1 showed a stable course. Conclusion: Early intervention with emollients in children with dry skin condition and atopic predisposition may improve their skin condition during daily emollient application. PIPJ-based formulations may be helpful to maintain skin barrier integrity.

show abstract

Section: Discussionmentioning

confidence: 99%

Children with Dry Skin and Atopic Predisposition: Daily Use of Emollients in a Participant-Blinded, Randomized, Prospective Trial

Schario

Lünnemann²,

Stroux³

et al. 2014

Skin Pharmacol Physiol

View full text Add to dashboard Cite

show abstract

“…The fresh fruits are widely consumed, and parts are used as functional foods, therapeutics, and animal food (Feugang et al, 2006). Many studies (Deters et al, 2012;Feugang et al, 2010;Kim et al, 2012;Tesoriere et al, 2004;Zou et al, 2005) have shown that cactus pears can reduce oxidative stress and may prevent cancer.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of antidiabetic properties of cactus pear seed oil in rats

Berraaouan

Ziyyat

Mekhfi

et al. 2014

Pharmaceutical Biology

View full text Add to dashboard Cite

Context: Cactus pear (Opuntia ficus-indica (L.) Mill. (Cactaceae)) is a medicinal plant widely used to treat diabetes. Objective: This work investigates the hypoglycemic and antihyperglycemic effect of cactus pear seed oil (CPSO), its mechanism of action, and any toxic effects. Materials and methods: The hypoglycemic effect of CPSO was evaluated in groups of six healthy Wistar rats given 1 or 2 ml kg À1 orally and compared with groups receiving glibenclamide (2 mg kg À1 ) or water. Glycemia was determined after 30, 60, 120, 240, and 360 min. The antihyperglycemic effect of CPSO was determined in healthy rats and in streptozotocin-induced diabetic rats (STZ); normal rats received 0.8 ml kg À1 CPSO, while diabetic rats received 1 ml kg À1 CPSO, their controls received water or 2 mg kg À1 glibenclamide. For the antihyperglycemic effect evaluation, all the animals were fasted for 16 h before treatment and received glucose orally at 1 g kg À1 30 min after treatment; blood was taken after 30, 90, 150, and 210 min. Intestinal glucose absorption was estimated in rat jejunum perfused with a solution containing 5.55 mmol l À1 glucose. Acute toxicity was determined in albino mice that received oral or intraperitoneal doses of 1, 3, or 5 ml kg À1 CPSO. Results: CPSO (p.o.) decreased postprandial hyperglycemia (60 min after glucose loading), 40.33% and 16.01%, in healthy and STZ-diabetic glucose-loaded rats, respectively. CPSO, also, significantly decreased intestinal glucose absorption by 25.42%. No adverse effects were seen in mice administered CPSO at up to 5 ml kg À1. Conclusion: CPSO is antihyperglycemic. The effect can be explained partly by inhibition of intestinal glucose absorption.

show abstract

“…Also, leaves of the ice plant are used in treatment of ascites, dysentery and diseases of the liver and kidney. It is used in dermatologicl and cosmetic preparations [9]. In Europe, the fresh juice has been used to treat water retention and painful urination and to soothe lung inflammation [10].…”

Section: Introductionmentioning

confidence: 99%

Ecology and development of Mesembryanthemum crystallinum L. in the Deltaic Mediterranean coast of Egypt

El-Gawad

Shehata

2014

Egyptian Journal of Basic and Applied Sciences

View full text Add to dashboard Cite

Available online xxxKeywords: Ecology Halophyte Mesembryanthemum crystallinum Relative growth rate Nile delta Conservation a b s t r a c t Ice plant (Mesembryanthemum crystallinum L.) is an important stress-tolerant halophyte distributed in saline areas along the Mediterranean coast of the Nile delta, Egypt. Plant communities dominated by M. crystallinum were studied in different habitats. The application of TWINSPAN classification based on 77 species recorded in 50 stands, led to the recognition of four vegetative groups, which are categorized under three communities. The first is salt marsh community co-dominated by M. crystallinum and Senecio glaucus L. The second is sand dune community dominated by Hordium murinum L. The third is sand flat community dominated by M. crystallinum. Electrical conductivity (EC), sodium ion concentration, Sodium Absorption Ratio (SAR) and sand fraction are the main controlling factors in the distribution of the different vegetative community. The distribution of M. crystallinum community was influenced by calcium carbonate, pH, E.C. and calcium.Various growth parameters including root, shoot and total fresh weight, diameter, leaf area, number of flowers and fruits were measured at two-week interval in the three habitats (sand dune, sand flat and salt marsh). The sand dune and salt marsh habitats, which are threatened by anthropogenic activities, were optimizing growth, flowering and fruiting of M. crystallinum.

show abstract

Time-dependent bioactivity of preparations from cactus pear (Opuntia ficus indica) and ice plant (Mesembryanthemum crystallinum) on human skin fibroblasts and keratinocytes

Cited by 22 publications

References 19 publications

Children with Dry Skin and Atopic Predisposition: Daily Use of Emollients in a Participant-Blinded, Randomized, Prospective Trial

Children with Dry Skin and Atopic Predisposition: Daily Use of Emollients in a Participant-Blinded, Randomized, Prospective Trial

Evaluation of antidiabetic properties of cactus pear seed oil in rats

Ecology and development of Mesembryanthemum crystallinum L. in the Deltaic Mediterranean coast of Egypt

Contact Info

Product

Resources

About