Providers of Emergency Medical Services (EMS) are typically concerned with keeping response times short. A powerful means to ensure this, is to dynamically redistribute the ambulances over the region, depending on the current state of the system. In this paper, we provide new insight in how to optimally (re)distribute ambulances. We study the impact of (1) the frequency of redeployment decision moments, (2) the inclusion of busy ambulances in the state description of the system, and (3) the performance criterion on the quality of the distribution strategy. In addition, we consider the influence of the EMS crew workload, such as (4) chain relocations and (5) time bounds, on the execution of an ambulance relocation. To this end, we use trace-driven simulations based on a real-life dataset of ambulance providers in the Netherlands. In doing so, we differentiate between rural and urban regions, which typically face different challenges when it comes to EMS. Our results show that: (1) taking the classical 0-1 performance criterion for assessing the fraction late arrivals only differs slightly from taking expert-opinion based S-curve for evaluating *