Abstract:Background: Crystalline silica is an important cause of serious pulmonary diseases. The relationship between this hazard and various physicochemical parameters of crystalline silica has been studied for more than a century, and the toxic potential of silica is known to be associated with its surface properties. However, no in vivo dataset has yet been accumulated to clarify the relevance of this, especially regarding longer term effects. To provide new insights into these longer term effects, we performed sing… Show more
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