Time Analysis of Corneal Endothelial Cell Density after Cataract Extraction

Management of Corneal Decompensation 4 Decades After Sputnik Intraocular Lens Implantation

“…This was attributed to surgical trauma at the time of iris-clip IOL implantation. 7 Another study also found that endothelial cell densities in the eyes with Sputnik IOLs decreased immediately after surgery and then continued to fall at the same rate as those of the aphakic and unoperated phakic fellow eye controls during follow-up periods ranging from 3 to 7 years, suggesting that corneal decompensation was most likely to occur in the early postoperative period after implantation of a Sputnik IOL because of surgical trauma at the time of IOL implantation. 8 These findings concurred with those of Price et al, 11 comparing the Fyodorov 4-loop iris-clip IOL and the Binkhorst 2-loop iridocapsular IOL, in that they demonstrated that the greatest cell loss had occurred by 1 month postoperatively, and thereafter, no rapid loss was apparent.…”

“…1 However, corneal decompensation was a recognized complication following implantation of the Sputnik IOL. This was shown to be because of endothelial trauma secondary to excessive manipulation at the time of primary IOL implantation 7,8 or because of postoperative dislocation of the IOLs. 9 With regard to the effect of iris-clip IOLs on the corneal endothelium, it is believed that mechanical trauma at the time of surgery contributes to more loss of endothelial cells with iris-clip IOLs.…”

“…Moreover, corneal decompensation associated with Sputnik IOLs was shown to be secondary to excessive manipulation during IOL implantation, rather than because of the presence of the IOL itself. 7,8 Spontaneous dislocation, which was reported in 5% to 10% of patients with Sputnik IOLs, was also a common cause of corneal decompensation. 9 However, in vivo studies showed that the PMMA material in the eye remains stable for up to 42 years.…”

Endothelial Cell Damage after Intracapsular Cataract Extraction and Primary Anterior Chamber Pseudophakos Implantation

“…This percentage may seem high but all authors who have studied endothelial cell loss com pared only endothelial cell counts of a re stricted central corneal field without consi dering changes in the cell density of the entire cornea and also in the vertical axis [Bourne and Kaufman, 1976b, c;Hirst el al.. 1977;Galin et al, 1979], Olsen [1980] em phasizes that the cell density should be lower in the upper part of the operated eyes. The rather high cell loss recorded in this study seems more understandable considering that the mean value in different areas was studied and confirms Olsen' s [1980] findings.…”

“…But it has been considered more likely to com promise the corneal endothelium than regu lar cataract surgery [Neetens et al, 1979;Binder et al, 1976;Bourne and Kaufman, 1976b, c;Cheng et al, 1977;Hirst et al, 1977;Galin, 1979;Olsen. 1980;Olsen and Eriksen, 1980].…”