Exercise-related syncope without organic heart disease has frequently been reported in young athletes [2,5,[9][10][11]14]. The exact incidence of idiopathic exercise-related syncope among young athletes is not known. Calkins et al. and Colivicchi et al. found that after a thorough cardiac evaluation athletes with an exertional-related syncope could safely continue to participate in athletics [2,3]. Tilt-table testing may be a useful diagnostic tool provoking syncope in 41 % of 24 athletes and up to 79 % after isoproterenol infusion [5]. Idiopathic exercise-related syncope has been reported to result from hypotension together with a normal HR, tachycardia, bradycardia or asystole [2,9]. The pathophysiology of this condition is poorly understood [9]. Atenolol, hydrofludrocortisone, disopyramide, transdermal scopolamine and increased salt intake have been recommended as treatment for exercise-related syncope [2,5,10,11,13]. To our knowledge this is the first report of a beneficial effect of water drinking for this condition.A 20-year-old male pupil of a sporting school had had attacks of lightheadedness over several months. The first time he felt unsteady and fell to the ground when he dismounted his bicycle after 1-hour of moderate exercise. In addition, he had chest pain and was short of breath. He was not certain whether or not he had passed out. Nobody had witnessed the event. For two hours afterwards he complained of unclear vision as if "looking through salad oil". He had not been incontinent, had sustained no bruises and no tongue bite. Later, similar attacks occurred during light cycling, after competition skating, after skiing and during miction after exercise. 26 21 43 Fax: +31-71/5 24 82 05 E-Mail: R.D.Thijs@lumc.nl s Abstract We report a 20-yearold sportsman with frequent attacks of lightheadedness, chest pain, blurred vision and falls during and shortly after exercise. Cardiac and pulmonal evaluation and routine autonomic function tests were normal apart from a relatively high resting heart rate (70 bpm) compared to endurance-trained men. In view of the relation to exercise, the patient was asked to cycle with maximal effort on an ergometer with continuous blood pressure (BP), heart rate (HR) and electroencephalogram (EEG) registration. Immediately after cessation of exercise a brief hypotensive period (75/45 mmHg) occurred together with sinus tachycardia (180 bpm) during which the patient experienced his typical complaints. We hypothesized that our patient's symptoms were primary related to sympathetic failure. As water drinking has been demonstrated to raise sympathetic activity rapidly, we undertook a second cycling test after ingestion of 1000 mL tap water. Symptoms nor hypotension recurred. Because of the short lasting pressor effect and its minimal side effects, we suggest water drinking as simple and possible effective therapy for idiopathic exercise-related syncope.s Key words syncope · exercise · water · treatment