Tijdig herkennen en behandelen van borderlineproblematiek bij jongeren met MBT-early

Hutsebaut, Joost; Feenstra, Dineke; Keur, Ellen; Schäfer, Benjamin; Bales, Dawn

doi:10.1007/s12485-017-0216-6

Cited by 5 publications

(8 citation statements)

References 25 publications

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“…The sample size is determined by the predicted difference between the groups on the primary outcome, the BPDSI-IV-ado [ 46 ]. Consistent with previous studies on MBT for adolescents [ 43 , 64 ] and MBT for adolescents compared with treatment as usual [ 27 ], we expect a medium effect size (Cohen’s d = 0.50) difference between MBT-early and CBT. Based on the BPDSI-IV-ado and with a two-sided α = 0.05, a power of 0.80 and a correlation of 0.50 between the repeated measures, based on Bales et al [ 65 ] and Hutsebaut et al [ 43 ], we require 59 participants in each treatment group (118 in total) with at least 1 follow-up measurement.…”

Section: Methods: Participants Interventions and Outcomessupporting

confidence: 88%

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The (cost-)effectiveness of early intervention (MBT-early) versus standard protocolized treatment (CBT) for emerging borderline personality disorder in adolescents (the EARLY study): a study protocol for a randomized controlled trial

Remeeus,

Clarke,

Feenstra

et al. 2024

Trials

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Background Although clinical guidelines prioritize the treatment of depression and anxiety in young persons, there is accumulating evidence that the presence of symptoms of borderline personality disorder (BPD) is associated with the limited effectiveness of these standard treatments. These findings stress the need for interventions addressing early-stage BPD in young people with presenting symptoms of anxiety and depressive disorders. The aim of this study is to investigate the (cost-)effectiveness of an early intervention programme for BPD (MBT-early) compared to first-choice psychological treatment for depression and anxiety according to Dutch treatment guidelines (CBT), in adolescents with either depression, anxiety, or both, in combination with early-stage BPD. Methods This study is a multi-centre randomized controlled trial. A total of 132 adolescents, presenting with either depression, anxiety, or both and significant BPD features will be randomized to either MBT-early or CBT. The severity of BPD, symptoms of depression and anxiety, personality, social and academic functioning, and quality of life will be assessed at baseline, end of treatment, and at 12-, 18-, and 24-month follow-up, along with medical costs and costs of productivity losses for cost-effectiveness analyses. Discussion This study will provide an empirical evaluation of the potential surplus value of early intervention in young people for whom treatment oriented at common mental disorders like anxiety and depression may be insufficient given their underlying personality problems. Trial registration Netherlands Trial Register, NL9569. Registered on June 15, 2021.

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Section: Methods: Participants Interventions and Outcomessupporting

confidence: 88%

“…Several types of MBT for BPD are empirically supported [ 40 – 42 ]. MBT-early, developed at de Viersprong and implemented since 2014, has offered preliminary support from a small naturalistic pilot study [ 43 ].…”

Section: Methods: Participants Interventions and Outcomesmentioning

confidence: 99%

The (cost-)effectiveness of early intervention (MBT-early) versus standard protocolized treatment (CBT) for emerging borderline personality disorder in adolescents (the EARLY study): a study protocol for a randomized controlled trial

Remeeus,

Clarke,

Feenstra

et al. 2024

Trials

Self Cite

View full text Add to dashboard Cite

show abstract

“…Consistent with previous studies on MBT for adolescents (43,64) and MBT for adolescents compared with treatment as usual ( 27), we expect a medium effect size (Cohen's d = 0.50) difference between MBT-early and CBT. Based on the BPDSI-IV-ado and with a two-sided α = 0.05, a power of 0.80 and a correlation of 0.50 between the repeated measures, based on Bales et al ( 65) and Hutsebaut et al (43), we require 59 participants in each treatment group (118 in total) with at least one follow-up measurement. Because of the vulnerable and unpredictable target population, we anticipate a 10% attrition rate and therefore intend to recruit at least 66 participants per group.…”

Section: Sample Size {14}supporting

confidence: 88%

“…Several types of MBT for BPD are empirically supported (40)(41)(42). MBT-early, developed at de Viersprong and implemented since 2014, has offered preliminary support from a small naturalistic pilot study (43).…”

Section: Mbt-earlymentioning

confidence: 99%

The (cost-)effectiveness of early intervention (MBT-early) versus standard protocolized treatment (CBT) for emerging borderline personality disorder in adolescents (the EARLY study): a study protocol for a randomized controlled trial

Remeeus,

Clarke,

Feenstra

et al. 2024

Preprint

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View full text Add to dashboard Cite

Background: Although clinical guidelines prioritize the treatment of depression and anxiety in young persons, there is accumulating evidence that the presence of symptoms of borderline personality disorder (BPD) is associated with limited effectiveness of these standard treatments. These findings stress the need for interventions addressing early-stage BPD in young people with presenting symptoms of anxiety and depressive disorders. The aim of this study is to investigate the (cost-)effectiveness of an early intervention program for BPD (MBT-early) compared to first-choice psychological treatment for depression and anxiety according to Dutch treatment guidelines (CBT), in adolescents with either depression, anxiety, or both, in combination with early stage BPD. Methods: This study is a multi-centre randomized controlled trial. A total of 132 adolescents, presenting with either depression, anxiety, or both and significant BPD features will be randomized to either MBT-early or CBT. Severity of BPD, symptoms of depression and anxiety, personality, social and academic functioning, and quality of life will be assessed at baseline, end of treatment, and at 12-, 18-, and 24-monts follow-up, along with medical costs and costs of productivity losses for cost-effectiveness analyses. Discussion: This study will provide an empirical evaluation of the potential surplus value of early intervention in young people for whom treatment oriented at common mental disorders like anxiety and depression may be insufficient given their underlying personality problems. Trial registration: Netherlands Trial Register: NL9569. Registered June 15, 2021.

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“…These programs are often time-limited and focused at empowerment. Programs like Helping Young People Early-Cognitive Analytic Therapy (Chanen et al, 2008), and Mentalization-Based Treatment–early (Hutsebaut, Feenstra, Keur, Schäfer, & Bales, 2017) were specifically designed to meet the needs of young people with emerging BPD and their families. Stage I programs could also be developed for persons in late adulthood, with a subthreshold BPD, preventing the development of a late onset BPD.…”

Section: Health Managementmentioning

confidence: 99%

Managing borderline personality disorder from a life course perspective: Clinical staging and health management.

Hutsebaut

Videler

Verheul

et al. 2019

Personality Disorders: Theory, Research, and Treatment

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Personality disorders change phenomenologically throughout the life course, in interaction with biological, psychological, and social events. In this article, we present a life course perspective on borderline personality disorder (BPD), based on clinical staging (conditional stimulus [CS]) and health management (HM). CS is presented as an alternative to the traditional categorical classification, providing improved opportunities to assess the severity of borderline impairment throughout the life course. It is primarily proposed as a heuristic strategy to guide design and selection of appropriate treatment according to the stage of disease progression. In addition, we introduce the concept of HM in the field of BPD, to organize continuous and coordinated health care management for patients with (emerging) BPD. HM redirects the exclusive focus on curative treatment of late-stage disorders to the broad spectrum of preventive, curative, and care interventions necessary to respond to the various needs in the different stages of BPD throughout the life course. Combining clinical staging and HM could provide a more effective and efficient framework for organizing mental health care for BPD.

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Tijdig herkennen en behandelen van borderlineproblematiek bij jongeren met MBT-early

Cited by 5 publications

References 25 publications

The (cost-)effectiveness of early intervention (MBT-early) versus standard protocolized treatment (CBT) for emerging borderline personality disorder in adolescents (the EARLY study): a study protocol for a randomized controlled trial

The (cost-)effectiveness of early intervention (MBT-early) versus standard protocolized treatment (CBT) for emerging borderline personality disorder in adolescents (the EARLY study): a study protocol for a randomized controlled trial

The (cost-)effectiveness of early intervention (MBT-early) versus standard protocolized treatment (CBT) for emerging borderline personality disorder in adolescents (the EARLY study): a study protocol for a randomized controlled trial

Managing borderline personality disorder from a life course perspective: Clinical staging and health management.

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