Tíðni einkenna og meðferð þeirra á síðasta sólarhring lífs hjá deyjandi sjúklingum á Landspítala og á hjúkrunarheimilum

Halfdanardottir, Svandis Iris; Ólafsdóttir, Kristín Lára; Sigurðardóttir, Valgerður

doi:10.17992/lbl.2017.05.135

LBL

2017

DOI: 10.17992/lbl.2017.05.135

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Tíðni einkenna og meðferð þeirra á síðasta sólarhring lífs hjá deyjandi sjúklingum á Landspítala og á hjúkrunarheimilum

Svandis Iris Halfdanardottir¹,

Kristín Lára Ólafsdóttir²,

Valgerður Sigurðardóttir³

Abstract: A large number of patients have symptoms in the last 24 hours of life both in hospital and in nursing homes. Symptom control can be improved by adjusting morphine doses to patients need, using regular doses of benzodiazepine for agitation and better use of anticholinergic medication for death rattle. Key words: symptoms, medication, dying patients, last 24 hours of life, hospital, nursing homes. Correspondence: Svandis Iris Halfdanardottir, svaniris@landspitali.is.

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2024

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Transition to end-of-life care in patients with neurological diseases in an acute hospital ward

Jonsdottir,

Haraldsdottir,

Vilhjalmsson

et al. 2024

BMC Neurol

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Background Transitioning to end-of-life care and thereby changing the focus of treatment directives from life-sustaining treatment to comfort care is important for neurological patients in advanced stages. Late transition to end-of-life care for neurological patients has been described previously. Objective To investigate whether previous treatment directives, primary medical diagnoses, and demographic factors predict the transition to end-of-life care and time to eventual death in patients with neurological diseases in an acute hospital setting. Method All consecutive health records of patients diagnosed with stroke, amyotrophic lateral sclerosis (ALS), and Parkinson’s disease or other extrapyramidal diseases (PDoed), who died in an acute neurological ward between January 2011 and August 2020 were retrieved retrospectively. Descriptive statistics and multivariate Cox regression were used to examine the timing of treatment directives and death in relation to medical diagnosis, age, gender, and marital status. Results A total of 271 records were involved in the analysis. Patients in all diagnostic categories had a treatment directive for end-of-life care, with patients with haemorrhagic stroke having the highest (92%) and patients with PDoed the lowest (73%) proportion. Cox regression identified that the likelihood of end-of-life care decision-making was related to advancing age (HR = 1.02, 95% CI: 1.007–1.039, P = 0.005), ischaemic stroke (HR = 1.64, 95% CI: 1.034–2.618, P = 0.036) and haemorrhagic stroke (HR = 2.04, 95% CI: 1.219–3.423, P = 0.007) diagnoses. End-of-life care decision occurred from four to twenty-two days after hospital admission. The time from end-of-life care decision to death was a median of two days. Treatment directives, demographic factors, and diagnostic categories did not increase the likelihood of death following an end-of-life care decision. Conclusions Results show not only that neurological patients transit late to end-of-life care but that the timeframe of the decision differs between patients with acute neurological diseases and those with progressive neurological diseases, highlighting the particular significance of the short timeframe of patients with the progressive neurological diseases ALS and PDoed. Different trajectories of patients with neurological diseases at end-of-life should be further explored and clinical guidelines expanded to embrace the high diversity in neurological patients.

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Transition to end-of-life care in patients with neurological diseases in an acute hospital ward

Jonsdottir,

Haraldsdottir,

Vilhjalmsson

et al. 2024

BMC Neurol

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show abstract

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Tíðni einkenna og meðferð þeirra á síðasta sólarhring lífs hjá deyjandi sjúklingum á Landspítala og á hjúkrunarheimilum

Cited by 1 publication

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Transition to end-of-life care in patients with neurological diseases in an acute hospital ward

Transition to end-of-life care in patients with neurological diseases in an acute hospital ward

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