Tibetan medicine Liuwei Muxiang pills (LWMX pills) effectively protects mice from chronic non-atrophic gastritis

Potential Mechanism of Tibetan Medicine Liuwei Muxiang Pills against Colorectal Cancer: Network Pharmacology and Bioinformatics Analyses

“…In addition, it was suggested that a herbal preparation of Aucklandiae Radix can effectively ameliorate 5-FU-induced gastrointestinal mucositis in CRC chemotherapy [ 26 ]. Notably, a recent mouse-model-based study by Dhondrup et al proved that LWMX pills are able to treat chronic gastritis and prevent gastric cancer progression by inhibiting inflammation and oxidative stress [ 15 ]. Despite TTM practitioners commonly prescribing LWMX pills for anti-CRC therapy, the molecular mechanism of this medication had not yet been fully elucidated.…”

“…According to TTM theory, LWMX pills function by “smoothing blood flow, clearing stomach fire, and removing blood stasis”, which means that LWMX pills have anti-inflammatory and anticancer effects, especially in gastrointestinal diseases. Several previous studies have reported LWMX pills’ effectiveness and potential mechanisms in treating gastrointestinal inflammation and carcinoma [ 15 , 16 , 17 ]. Nevertheless, the mechanism through which LWMX pills function in CRC remains unexplored.…”

Influence of helicobacter pylori on composition and function of gastric microbiota in patients with chronic non-atrophic gastritis

“…The main goal of CNAG treatment is to improve clinically related symptoms, remove etiology, and protect gastric mucosa, in order to enhance patients' life satisfaction [ 3 ]. Moreover, to prevent the progress of CNAG and reduce or prevent persistent gastric atrophy, intestinal lining cells transformation, intraepithelial neoplasia and stomach cancer is also imperative [ 4 ].…”