Thyrotropic pituitary adenoma with plurihormonal immunoreactivity

Vora, Tarang K.; Karunakaran, Sudish

doi:10.4103/neuroindia.ni_577_16

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“…Our patient did not show any clinical features except blurred vision. Inadequate peptide synthesis by the tumor tissue may determine the deficiency of the corresponding clinical and biochemical symptoms (20). In order to control high levels of prolactin after the second operation and the size of adenoma, cabergoline treatment was initiated, and radiotherapy was applied.…”

Section: Discussionmentioning

confidence: 99%

A Case of Plurihormonal Pituitary Giant Macroadenoma

Özışık¹,

YÜREKLİ²,

Ertan³

et al. 2021

Turk J Endocrinol Metab

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Section: Discussionmentioning

confidence: 99%

A Case of Plurihormonal Pituitary Giant Macroadenoma

Özışık¹,

YÜREKLİ²,

Ertan³

et al. 2021

Turk J Endocrinol Metab

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Plurihormonal Pituitary Tumor of Pit-1 and SF-1 Lineages, with Synchronous Collision Corticotroph Tumor: a Possible Stem Cell Phenomenon

et al. 2019

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Pathogenesis, clinical features, and treatment of plurihormonal pituitary adenoma

Cai,

Liu,

Zhao

et al. 2024

Front. Neurosci.

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Plurihormonal pituitary adenoma (PPA) is a type of pituitary tumor capable of producing two or more hormones and usually presents as an aggressive, large adenoma. As yet, its pathogenesis remains unclear. This is the first study to systematically summarize the underlying pathogenesis of PPA. The pathogenesis is related to plurihormonal primordial stem cells, co-transcription factors, hormone co-expression, differential gene expression, and cell transdifferentiation. We conducted a literature review of PPA and analyzed its clinical characteristics. We found that the average age of patients with PPA was approximately 40 years, and most showed only one clinical symptom. The most common manifestation was acromegaly. Currently, PPA is treated with surgical resection. However, recent studies suggest that immunotherapy may be a potentially effective treatment.

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Thyrotropic pituitary adenoma with plurihormonal immunoreactivity

Cited by 3 publications

References 0 publications

A Case of Plurihormonal Pituitary Giant Macroadenoma

A Case of Plurihormonal Pituitary Giant Macroadenoma

Plurihormonal Pituitary Tumor of Pit-1 and SF-1 Lineages, with Synchronous Collision Corticotroph Tumor: a Possible Stem Cell Phenomenon

Pathogenesis, clinical features, and treatment of plurihormonal pituitary adenoma

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