Thyroiditis and Chromosomal Anomalies

Thyroid dysfunction in Down syndrome: A review

“…One group of investigators found that there is an increased incidence of maternal thyroid disease in mothers of newborns with Down's syndrome (Fialkow et al 1965;Dallaire and Flynn 1967;Vanhaelst et al 1970;Fialkow et al 1971). However, recent studies have found no increase in the prevalence of thyroid antibodies in mothers of infants with Down's syndrome compared to controls (summarised in Torfs et al 1990).…”