Thyroid surgery in children and adolescents

Astl, Jaromı́r; Dvořáková, Marcela; Vlček, Petr; Vesely, David L.; Matucha, Petr; Betka, Jan

doi:10.1016/j.ijporl.2004.04.024

Cited by 27 publications

(22 citation statements)

References 20 publications

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“…In case of unilateral disease, some studies recommended unilateral resection in both adults and children [45,46]. For unilateral resection, transient hypocalcemia was reported in 0-18% of patients, voice hoarseness in 1-6%, and hematoma in 0-1%; moreover, transient hypoparathyroidism is uncommon [10,16,47,48].…”

Section: Discussionmentioning

confidence: 99%

Total Thyroidectomy versus Bilateral Subtotal Thyroidectomy for Bilateral Multinodular Nontoxic Goiter: A Meta-Analysis

Li²,

Zhou³

2016

ORL

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Aim: The aim of this meta-analysis is to assess and validate the feasibility and safety of total thyroidectomy (TT) when compared to bilateral subtotal thyroidectomy (BST) for bilateral multinodular nontoxic goiter (BMNG). Materials and Methods: PubMed, Web of Knowledge, and Ovid's database were searched for studies published in English language between January 1990 and December 2014. A meta-analysis was performed to compare the complications and recurrences of TT versus BST. The search terms used were ‘total thyroidectomy', ‘bilateral subtotal thyroidectomy', ‘multinodular nontoxic goiter' and ‘randomized clinical trial'. The reference lists of relevant studies were checked manually to locate any missing studies. Results: Four trials with a total of 1,078 patients were analyzed. Although the incidence of transient hypoparathyroidism was higher in TT than in BST (OR = 2.59, 95% CI [1.58-4.24], p = 0.0002), TT was associated with a significantly lower incidence of recurrence (OR = 0.04, 95% CI [0.01, 0.17], p < 0.0001). There were no statistically significant differences for the presence of transient/permanent recurrent laryngeal nerve palsy and permanent hypoparathyroidism between the two groups. Conclusion: TT is a feasible and safe procedure for patients with BMNG. Although TT involves a significantly higher risk of postoperative transient hypoparathyroidism, it has a lower recurrence rate than BST.

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Section: Discussionmentioning

confidence: 99%

Total Thyroidectomy versus Bilateral Subtotal Thyroidectomy for Bilateral Multinodular Nontoxic Goiter: A Meta-Analysis

Li²,

Zhou³

2016

ORL

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“…Con cirugía subtotal se desarrolla hipotiroidismo en 60% de los pacientes pero aumenta la recurrencia de hipertiroidismo en un 10-15%. Las complicaciones propias de la cirugía se reducen en manos de un cirujano experto, sin embargo, se describe hipoparatiroidismo permanente en 1,75%, lesiones del nervio laringeo recurrente (2%) y queloide de la cicatriz en un 12,3% 26 . La mortalidad es de 1/1.000 tiroidectomías realizadas 3 .…”

Section: Discussionunclassified

Hipertiroidismo en niños y adolescentes

et al. 2009

Rev. chil. pediatr.

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Hyperthyroidism in children and adolescentsBackground: Hyperthyroidism (HT) prevalence is 0.1/100,000 children and 1/100,000 adolescents and Graves Disease is the most frequent etiology. Objective: To evaluate the clinical presentation, etiology and treatment in hyperthyroid children. Method: Retrospective review of clinical charts of children under 15 years-old, between June 2004 and August 2005. Hyperthyroidism diagnosis was performed with suppressed TSH and increased thyroid hormones levels. Etiological study was done by TRAb, ATPO, ATG, thyroid echotomography and I

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“…Thyroid lobectomy with isthmusectomy for a solitary toxic nodule in pediatric patients is currently performed (Astl et al, 2004;Canadian, 2008). Although radioactive iodine therapy and anti-thyroid medications are efficacious in a certain percentage of patients, many pediatricians believe that the benefits of surgical resection outweigh the risks of receiving radioactive iodine therapy (RAI), the substantial rate of permanent hypothyroidism, noncompliance with medication, and need for immediate relief of hyperthyroid symptoms (school and social performance) in this particular age group (Sherman et al, 2006).…”

Section: Toxic Nodulesmentioning

confidence: 99%