Thyroid Imaging Reporting and Data System Risk Stratification of Thyroid Nodules: Categorization Based on Solidity and Echogenicity

Na, Dong Gyu; Baek, Jung Hwan; Sung, Jin Yong; Kim, Ji Hoon; Kim, Tae Yong; Choi, Young Jun; Seo, Hyobin

doi:10.1089/thy.2015.0460

Cited by 158 publications

(193 citation statements)

References 31 publications

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“…Recently, similar recommendations have been issued by the Korean Society of Thyroid Radiology, the American Thyroid Association, the American Association of Clinical Endocrinologists, the American College of Endocrinology, and the Italian Associazione Medici Endocrinologi [16-18]. None of these recommendations have been validated in large-scale prospective studies, and all systems are mainly based on papillary thyroid cancers (PTCs).…”

Section: Background and Objectivesmentioning

confidence: 99%

“…Marked hypoechogenicity has the lowest sensitivity of the four features, and is only specific if the nodule is solid and not the scar of a healed cyst [34]. The value of these features is also dependent on composition [16]. In partially cystic nodules, microcalcifications are the best predictor of malignancy, whereas other features seem less significant [16].…”

Section: Eu-tirads: Us Classification System For Risk Of Thyroid Carcmentioning

confidence: 99%

“…The value of these features is also dependent on composition [16]. In partially cystic nodules, microcalcifications are the best predictor of malignancy, whereas other features seem less significant [16]. The number of spiculations, lobulations, or punctate echogenic foci has to be taken into account to gain specificity, which increases with the number of these anomalies.…”

Section: Eu-tirads: Us Classification System For Risk Of Thyroid Carcmentioning

confidence: 99%

See 2 more Smart Citations

European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS

Russ¹,

Bonnema²,

Erdoğan³

et al. 2017

Eur Thyroid J

860

835

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Thyroid ultrasound (US) is a key examination for the management of thyroid nodules. Thyroid US is easily accessible, noninvasive, and cost-effective, and is a mandatory step in the workup of thyroid nodules. The main disadvantage of the method is that it is operator dependent. Thyroid US assessment of the risk of malignancy is crucial in patients with nodules, in order to select those who should have a fine needle aspiration (FNA) biopsy performed. Due to the pivotal role of thyroid US in the management of patients with nodules, the European Thyroid Association convened a panel of international experts to set up European guidelines on US risk stratification of thyroid nodules. Based on a review of the literature and on the American Association of Clinical Endocrinologists, American Thyroid Association, and Korean guidelines, the panel created the novel European Thyroid Imaging and Reporting Data System, called EU-TIRADS. This comprises a thyroid US lexicon; a standardized report; definitions of benign and low-, intermediate-, and high-risk nodules, with the estimated risks of malignancy in each category; and indications for FNA. Illustrated by numerous US images, the EU-TIRADS aims to serve physicians in their clinical practice, to enhance the interobserver reproducibility of descriptions, and to simplify communication of the results.

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Section: Background and Objectivesmentioning

confidence: 99%

Section: Eu-tirads: Us Classification System For Risk Of Thyroid Carcmentioning

confidence: 99%

Section: Eu-tirads: Us Classification System For Risk Of Thyroid Carcmentioning

confidence: 99%

See 1 more Smart Citation

European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS

Russ¹,

Bonnema²,

Erdoğan³

et al. 2017

Eur Thyroid J

860

835

View full text Add to dashboard Cite

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“…Researchers have recently attempted to validate this type of approach as an instrument for use in clinical practice, with some authors proposing different TI-RADS versions in selected populations (14)(15)(16)(17)(18)(19)(20).…”

Section: Introductionmentioning

confidence: 99%

Likelihood of malignancy in thyroid nodules according to a proposed Thyroid Imaging Reporting and Data System (TI-RADS) classification merging suspicious and benign ultrasound features

Delfim

Veiga

Vidal

et al. 2017

Arch. Endocrinol. Metab.

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Objective: The aim of this study was to describe the ultrasound features of benign and malignant thyroid nodules and evaluate the likelihood of malignancy associated with each feature according to the Bethesda System for Reporting Thyroid Cytopathology and histopathology. With this analysis, we propose a new TI-RADS classification system. Materials and methods: The likelihood of malignancy from ultrasound features were assessed in 1413 thyroid nodules according to the Bethesda System for Reporting Thyroid Cytopathology and histopathological findings. A score was established by attributing different weights to each ultrasound feature evaluated. Results: Features positively associated with malignancy in bivariate analysis received a score weight of +1. We attributed a weight of +2 to features which were independently associated with malignancy in a multivariate analysis and +3 for those associated with the highest odds ratio for malignancy (> 10.0). Hence, hypoechogenicity (graded as mild, moderate or marked, according to a comparison with the overlying strap muscle), microcalcification and irregular/microlobulated margin received the highest weights in our scoring system. Features that were negatively associated with malignancy received weights of -2 or -1. In the proposed system a cutoff score of 2 (sensitivity 97.4% and specificity 51.6%) was adopted as a transition between probably benign (TI-RADS 3) and TI-RADS 4a nodules. Overall, the frequency of malignancy in thyroid nodules according to the categories was 1.0% for TI-RADS 3, 7.8% for TI-RADS 4a, 35.3% for TI-RADS 4b, and 84.7% for TI-RADS 5. Conclusion: A newly proposed TI-RADS classification adequately assessed the likelihood of malignancy in thyroid nodules. Arch Endocrinol Metab. 2017;61(3):211-21.

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“…4. The proposed risk stratification system based on solidity and echogenicity will be useful for risk stratification and management decision of thyroid nodules [13]. 5.…”

Section: Thyroid Gland Thyroid Nodulesmentioning

confidence: 99%

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

et al. 2017

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Accurate differentiation of focal thyroid nodules (FTL) and thyroid abnormalities is pivotal for proper diagnostic and therapeutic work-up. In these two part articles, the role of ultrasound techniques in the characterization of FTL and evaluation of diffuse thyroid diseases is described to expand on the recently published World Federation in Ultrasound and Medicine (WFUMB) thyroid elastography guidelines and review how this guideline fits into a complete thyroid ultrasound exam.

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Thyroid Imaging Reporting and Data System Risk Stratification of Thyroid Nodules: Categorization Based on Solidity and Echogenicity

Cited by 158 publications

References 31 publications

European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS

European Thyroid Association Guidelines for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults: The EU-TIRADS

Likelihood of malignancy in thyroid nodules according to a proposed Thyroid Imaging Reporting and Data System (TI-RADS) classification merging suspicious and benign ultrasound features

Thyroid Ultrasound: State of the Art Part 1 – Thyroid Ultrasound reporting and Diffuse Thyroid Diseases

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