Thyroid Function Assay With Radioiodine. Iii. Clinical Test Results and Diagnostic Limits for Rate Constants 1

Menstrual Disorders in Patients With Thyrotoxicosis

“…Seven patients from this group were excluded because they were either prepubertal or pregnant at the time of presentation. The diagnosis of thyrotoxicosis in these patients was based on clinical evidence, together with the findings of elevated thyroidal clearance rates of I3lI (Oddie et al, 1955), elevated serum protein bound iodine estimations (P.B.I.) (Radcliff et al, 1964), and in most cases elevated tri-iodothyronine resin uptake tests (T3resin) by Abbott kit.…”

Endocrinology

“…A pertinent report by Albeaux Fernet et al described remission in Graves' disease following hypophysec tomy (357). Various refinements in the use of JIll as a diagnostic tool have been presented by Oddie et al (358), Rall (359) , and McConahey and co workers (360) .…”

Radioiodine Tracer Tests in the Diagnosis of Hyperthyroidism

“…The thyroid clearance test of Myant, Pochin, and Goldie (1949), however, is laborious in that it involves serial measurements over the gland and the measurement of radioiodine in the blood plasma; the uptake rate factor of Oddie, Meschan, and Wortham (1955) involves measurementsofthyroidal radioiodine at 1, 4, and 24 hours; while the thigh/neck clearance test of Foote and Maclagan (1951) and the uptake rate factors of the earlier studies at the Royal Melbourne Hospital' also depend on serial measurements. Pochin (1950) was the first to observe that a simple but efficient test would be an early comparison of the counting rate over the neck with that over the thigh following the administration of a tracer dose of radioiodine, and Rundle, Seldon, and Indyk (1956) have also found such an index to be useful.…”