Thyroid function and thyroid disorders during pregnancy: a review and care pathway

Delitala, Alessandro; Capobianco, Giampiero; Cherchi, Pl; Dessole, Salvatore; Delitala, G.

doi:10.1007/s00404-018-5018-8

Cited by 59 publications

(80 citation statements)

References 124 publications

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“…Thyroid-stimulating hormone (TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4 ), and then triiodothyronine (T 3 ) which promotes the metabolism of body tissues ( Magner, 2014 ). It promotes growth and the maturation of bones and the central nervous system, increase carbohydrates, lipids and protein metabolism ( Delitala et al., 2019 ).The decrease TSH in E. vermiculate may be due to disrupting effect of synthetic combined contraceptive drug. Prolactin (PRL), stimulates the mammary glands to produce milk which normally starts when levels of progesterone fall by the end of pregnancy and plays an important role in maternal behavior ( Lucas et al., 1998 ).…”

Section: Resultsmentioning

confidence: 99%

Usage of pharmaceutical contraceptive drug for controlling Eobania vermiculata snails by baits technique

El-Atti

Elsayed

Said

2020

Heliyon

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Section: Resultsmentioning

confidence: 99%

Usage of pharmaceutical contraceptive drug for controlling Eobania vermiculata snails by baits technique

El-Atti

Elsayed

Said

2020

Heliyon

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“…SCHyper does not appear to be associated with increased risks of maternal, obstetric, or neonatal morbidities, when compared to euthyroid pregnant women, and instead may even have decreased risks of gestational hypertension [65], [66]. Several recommendations advise that SCHyper in pregnancy does not necessarily require treatment and may be monitored [65], [66], [67]. However, SCHyper during weeks 4-8 of pregnancy has also been reported to be associated with a decreased incidence of abortion but is a risk factor for preeclampsia and placental abruption [68].…”

Section: Subclinical Hyperthyroidism In Pregnancymentioning

confidence: 99%

Subclinical Hyperthyroidism: A Review of the Clinical Literature

Tsai

Leung

2021

Endocrine Practice

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“…We considered that the main reasons might be related to using levothyroxine or propylthiouracil (PTU) once the hypothyroidism or hyperthyroidism was diagnosed. Many of previous studies showed that untreated hypothyroidism and hyperthyroidism can cause serious adverse consequences for the pregnant women and fetal [6,12,[21][22][23], however, if the maternal hyperthyroidism was adequately treated, prognosis was well [5,23]. According to the existing guidelines [7], all participants identi ed as overt hyperthyroidism and hypothyroidism were treated immediately and kept TSH in an ideal range continuously in our study.…”

Section: Discussionmentioning

confidence: 95%

Retrospective analysis of the effects induced by maternal thyroid dysfunction on obstetrical complications and outcomes

Sun

Wang

Fang

et al. 2020

Preprint

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Background: Abnormal concentrations of maternal thyroid hormones are risk factors for some obstetrical complications. However, the influence induced by different types of maternal thyroid dysfunction on obstetrical complications and outcomes is still controversial.Methods: A total of 17219 pregnant women were drawn for a thyroid function test, including TSH and fT4. All participants were divided into 7 groups, on the basis of their blood tested results, and their pregnancy outcomes were followed up. The isolated hypothyroxinemia group was further divided into 2 cohorts, according to whether they receive levothyroxine. Pregnant complications and outcomes in two cohorts were observed and analyzed.Results: A total of 2621 (15.22%)were identified to have abnormal thyroid function, including 1150 with subclinical hypothyroidism, 526 with gestational transient thyrotoxicosis (GTT), 419 with subclinical hyperthyroidism, 336 with isolated hypothyroxinemia, 78 with hyperthyroidism and 76 with hypothyroidism. Compare to control group, subclinical hypothyroidism, subclinical hyperthyroidism, isolated hypothyroxinemia and hypothyroidism groups presented higher incidence in one or more complications of pregnancy, while, GTT and drug-controlled hyperthyroidism had little significant effect on pregnancy complications. In isolated hypothyroxinemia group, there were no significant difference outcomes between cohorts using levothyroxine and not treatment.Conclusions: Our results showed a high incidence rate of thyroid dysfunction in pregnant women, and subclinical hypothyroidism is most common, followed by GTT. In general, pregnant women with thyroid dysfunction presented high risk of pregnancy complications. Isolated hypothyroxinemia in pregnant women is a matter of concern and treatment with levothyroxine couldn’t improve pregnancy outcomes and obstetrical complications.

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Thyroid function and thyroid disorders during pregnancy: a review and care pathway

Cited by 59 publications

References 124 publications

Usage of pharmaceutical contraceptive drug for controlling Eobania vermiculata snails by baits technique

Usage of pharmaceutical contraceptive drug for controlling Eobania vermiculata snails by baits technique

Subclinical Hyperthyroidism: A Review of the Clinical Literature

Retrospective analysis of the effects induced by maternal thyroid dysfunction on obstetrical complications and outcomes

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