Thyroid dysfunction induced by immune checkpoint inhibitors and tumor progression in neoadjuvant therapy for Non-Small Cell Lung Cancer: a case report and literature review
Abstract:BackgroundThe immune checkpoint inhibitors (ICIs) targeting anti-programmed death receptor 1 (PD-1) and its ligand (PD-L1) has shown promising value in resectable (stage I-IIIA) or potentially resectable (stage IIIB) non-small-cell lung cancer (NSCLC). However, the immune-related adverse events (irAEs) and tumor progression in neoadjuvant therapy are of great concern, which might result in surgical delay or failure to undergo resection. In addition, the association between the development of thyroid dysfunctio… Show more
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