Thyroid dysfunction and cardiovascular risk factors in Bulgarian adults

Abstract

<jats:title>Abstract</jats:title><jats:p>The aim of this study was to determine the prevalence of thyroid dysfunction and its association with cardiovascular risk factors in an adult Bulgarian population. 2402 subjects were studied, 1347 female, 20–94y (median: 48.0y) and 1055 male, 20–91y (median: 45.5y). Body weight, height, waist circumference, arterial blood pressure, TSH, FT4 and lipids were measured. Known hypothyroidism was reported by 53 subjects (2.2%) and hyperthyroidism by 20 (0.8%). New hypothyroidism was found in 98 (4.1%), [subclinical (3.2%), overt (0.9%)]. New hyperthyroidism was found in 68 (2.9%), [subclinical (2.5%), overt (0.4%)]. New diagnosis of hypothyroidism and hyperthyroidism was entered in 84% and 87% in male subjects and 60% and 65% in the females respectively. Arterial hypertension was present in 40% of the women and in 47% of the men (p&lt;0.001) and was more prevalent in hypothyroidism. Abdominal obesity and dyslipidemia were more prevalent in males and hypothyroid subjects. Arterial hypertension depended on age, gender and lipid status but not on thyroid function. CHD history depended on thyroid function and age. Conclusion: Most cases of thyroid dysfunction were undiagnosed, especially in the males. CV risk factors were more prevalent in the males with thyroid dysfunction a major determinant of CHD, but not hypertension.</jats:p>

The prevalence of the metabolic syndrome increases through the quartiles of thyroid stimulating hormone in a population-based sample of euthyroid subjects

“…The sample size and age structure were planned in correspondence with the age structure of the population as determined by the latest census in 2005 (44.5% young, 35.5% middle-aged and 20% elderly). The study population has been described in more detail elsewhere (15).…”

Color discrimination assessment in patients with hypothyroidism using the Farnsworth–Munsell 100 hue test

“…Hypofunction of the thyroid gland (hypothyroidism) is a condition in which the thyroid gland is not able to produce enough thyroid hormones. Hypothyroidism can be a serious disorder which affects a large number of individuals depending on age and gender [1,2,3]. It is more common in women than in men however the ratio can vary widely [2,3,4,5].…”

“…Hypothyroidism can be a serious disorder which affects a large number of individuals depending on age and gender [1,2,3]. It is more common in women than in men however the ratio can vary widely [2,3,4,5]. The effects of thyroid hormones on the brain are most prominent in perinatal development, and the absence or reduction of thyroid hormones limits the normal development of sensory organs [6][7][8][9].…”

Functional Limitations of Hyper and Hypothyroid Patients in INMOL Hospital Lahore, Pakistan

“…Thyroid disorder had an impact on the heartbeat and has been associated with the type of thyroid disease. Patients with hyperthyroidism reported fast heartbeat whereas it is slow among hypothyroid patients [25]. Effect on heartbeat is also associated with age and BMI.…”