2022
DOI: 10.1016/j.ijscr.2022.107358
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Thyroid angiosarcoma: A case report and review of literature

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“…They usually occur in the context of long-standing multinodular goiters [81,82], mainly in the alpine region although they have been described elsewhere [83,84]. While some authors have considered them as an anaplastic or undifferentiated carcinoma with angiomatoid characteristics [85][86][87], there is now broad consensus that angiosarcomas arise from endothelial cells, characterized by positivity for the CD31 marker and erythroblast transformation-specific related gene (ERG) [77,85,[88][89][90]. Clinical and radiological features are nonspecific.…”
Section: Angiosarcomamentioning
confidence: 99%
“…They usually occur in the context of long-standing multinodular goiters [81,82], mainly in the alpine region although they have been described elsewhere [83,84]. While some authors have considered them as an anaplastic or undifferentiated carcinoma with angiomatoid characteristics [85][86][87], there is now broad consensus that angiosarcomas arise from endothelial cells, characterized by positivity for the CD31 marker and erythroblast transformation-specific related gene (ERG) [77,85,[88][89][90]. Clinical and radiological features are nonspecific.…”
Section: Angiosarcomamentioning
confidence: 99%