Thyroid and Growth Hormone Axes Alteration in the Critically Ill Child

Branco, Ricardo Garcia; García, Pedro Celiny Ramos; Piva, Jefferson Pedro

doi:10.1007/978-1-4471-6416-6_11

Cited by 1 publication

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“…However, serum rT3 levels may be low or elevated in ESS. 12 Serum T3 and T4 levels are influenced by alterations in concentrations of thyroid hormone binding proteins. Therefore, serum FT3 and FT4 levels were measured to assess thyroid function in our study, and serum rT3 levels were not measured.…”

Section: Discussionmentioning

confidence: 99%

Euthyroid sick syndrome in children with diabetic ketoacidosis

Wang

2015

SMJ

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Objectives:To investigate characteristics of euthyroid sick syndrome (ESS) in children with diabetic ketoacidosis (DKA).Methods:This retrospective study was carried out between May 2010 and April 2013 at the Pediatric Department of Shandong Provincial Hospital, Shandong University, Shandong, China. Diabetic ketoacidosis children were divided into 2 groups: euthyroidism (group one, n=30) and ESS (group 2, n=40). C-peptide, glycosylated hemoglobin (HbA1c), bicarbonate, anion gap (AG), free triiodothyronine (FT3), free thyroxine (FT4), and thyrotropin (TSH) levels were measured before and after 7 days of insulin treatment. Daily blood glucose (BG) profiles were recorded.Results:Glycosylated hemoglobin, AG, the mean daily BG, and fasting blood glucose levels were higher, and bicarbonate, FT3, FT4, and TSH levels were lower in group 2 than in group one (all p<0.05). Free triiodothyronine (r=-0.593, p<0.001) and FT4 (r=-0.402, p=0.001) were negatively correlated with HbA1c. Free triiodothyronine (r=-0.438, p<0.001) and FT4 (r=-0.505, p<0.001) were negatively correlated with AG, and FT3 (r=0.503, p<0.001) and FT4 (r=0.448, p<0.001) were positively correlated with bicarbonate.Conclusion:Diabetic ketoacidosis children with ESS have poor diabetic control. Free thyroid hormones are associated with the severity of DKA.

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Section: Discussionmentioning

confidence: 99%

Euthyroid sick syndrome in children with diabetic ketoacidosis

Wang

2015

SMJ

View full text Add to dashboard Cite

show abstract

Thyroid and Growth Hormone Axes Alteration in the Critically Ill Child

Cited by 1 publication

References 63 publications

Euthyroid sick syndrome in children with diabetic ketoacidosis

Euthyroid sick syndrome in children with diabetic ketoacidosis

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