Abstract:Highlights• Thyroid and androgen hormone driven pathways in prostate cancer (PCa) are antagonized by μ-Crystallin (CRYM).• [18F]fluoromethylcholine uptake and prognostic values in PCa correlate with CRYM protein levels.• Reduced CRYM expression predicts early biochemical recurrence (BCR) in PCa patients.
AbstractAndrogen deprivation therapy (ADT) remains a key approach in the treatment of prostate cancer (PCa). However, PCa inevitably relapses and becomes ADT resistant. Besides androgens, there is evidence tha… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.