Thyroglossal duct cyst carcinoma: case report and review of the literature, with emphasis on CT findings

Samara, Christianna; Bechrakis, I.; Kavadias, S.; Παπαδοπουλοσ, Αντωνιοσ; Maniatis, V.; Strigaris, Kyriakos

doi:10.1007/s002340000402

Cited by 31 publications

(16 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Occurrence of nodules inside the cyst was the most frequent sign of TDCa and calcification, thickness and irregularity of the cyst wall also indicated carcinoma. Nevertheless, no specific radiographic sign can be detected in some cases of TDCa [19]. Only one case in our series has a multicystic appearance in CT.…”

Section: Discussioncontrasting

confidence: 50%

Diagnosis and treatment of thyroglossal duct carcinoma: Report of three cases with review of literatures

Sun

Guo

et al. 2008

Front. Med. China

View full text Add to dashboard Cite

Thyroglossal duct carcinoma, which is usually diagnosed postoperatively, is a rare malignant tumor arising in the thyroglossal duct cyst. The definitive diagnosis can be made only after microscopic examination. We retrospectively reviewed three cases of thyroglossal duct carcinoma diagnosed in Peking University School and Hospital of Stomatology from January 1986 to August 2006. Clinical and pathological features were investigated and the optimal treatment protocol was proposed. The constituent ratio of thyroglossal duct carcinoma among surgically excised thyroglossal duct lesions was 2.9%. The clinical presentation of thyroglossal duct carcinoma was very similar to that of its benign counterpart. Two cases were diagnosed as thyroglossal duct cyst prior to the operation, the remaining one as dermoid cyst. All three cases were diagnosed as papillary carcinoma of thyroid origin after microscopic examination. Primary thyroglossal duct carcinoma should conform to the following criteria: localization of the carcinoma to a clearly demonstrable thyroglossal duct cyst or tract; clinically or histologically confirmed absence of carcinoma of the thyroid gland. Papillary carcinoma is the most common histological type, which usually develops slowly with an excellent prognosis. The histological characteristics including: formation of papillary structure; nuclear morphological variations such as ground glass nuclei, pseudoinclusions, intranuclear grooves and filaments; concentrically calcified structures termed psammoma bodies which is regarded as a strong indication of papillary carcinoma; and positivity in immunohistological staining for thyroglobin. Sistrunk procedure of excision is the choice for treatment. A close follow-up is needed. In the presence of thyroid gland masses or cervical lymphadenopathy, thyroidectomy or neck dissection should be recommended. The effect of thyroid suppression therapy and radioactive iodine therapy is not conclusive.

show abstract

Section: Discussioncontrasting

confidence: 50%

Diagnosis and treatment of thyroglossal duct carcinoma: Report of three cases with review of literatures

Sun

Guo

et al. 2008

Front. Med. China

View full text Add to dashboard Cite

show abstract

“…Thyroglossal duct carcinoma, usually papillary adenocarcinoma, is an uncommon complication of TDC, occurring in less than 1% of cases. [16][17][18] Fistulas are also uncommon in TDCs but can occur after inflammation. 19 Regarding location, our results showed that most of the TDCs were midline, approximately similar to the results of the 2 previous studies (Table 1).…”

Section: Discussionmentioning

confidence: 99%

Sonographic Assessment of Thyroglossal Duct Cysts in Children

Kutuya¹,

Kurosaki²

2008

Journal of Ultrasound in Medicine

View full text Add to dashboard Cite

Abbreviations BCC, branchial cleft cyst; TDC, thyroglossal duct cyst he thyroglossal duct cyst (TDC) is one of the most common congenital neck masses occurring in children, representing approximately 70% of the congenital lesions that occur in the neck. 1,2Sonography is thought to be an ideal initial technique for the differential diagnosis of a neck mass. In the past, the TDC commonly had been known to be a midline anechoic cyst at the level of the hyoid bone.3-6 However, many variations of its sonographic features have been reported. 7,8 As a result, it is important to confirm the existence of a TDC in the differential diagnosis by means of preoperative sonographic examinations, but a correct diagnosis is often difficult to make. As far as we could determine, up to now there have only been 2 statistical investigations (by Wadsworth and Siegel 7 and Ahuja et al 8 ) regarding the sonographic appearance of TDCs in children. We thus thought that an additional investigation should be performed. Therefore, in this study we assessed the sonographic appearance in 36 children with Image PresentationObjective. The purpose of this study was to clarify the sonographic features of thyroglossal duct cysts (TDCs) in children. We also investigated how the presence of inflammation influences the sonographic appearance. Methods. We reviewed the sonograms from 36 children (0.5-14 years old) with pathologically proven TDCs. The lesions were evaluated for location, shape, internal echo pattern, internal septa, wall thickness, posterior enhancement, solid components, margins, and fistulas. The sonographic features of 7 lesions that pathologically showed inflammation were also investigated. Results. Most TDCs were midline (77.8%), were located at the hyoid bone (44.4%) or were infrahyoid (38.9%), showed posterior enhancement (77.8%), were unilocular (86.1%), lacked internal septa (91.7%), and had a thin wall (75%). None had a solid component. The internal echo patterns were classified into 4 types: anechoic (25%), homogeneously hypoechoic (16.7%), pseudosolid (16.7%), and heterogeneous (41.6%). Inflammation was confirmed in 78% of the lesions with wall thickening and 100% of the lesions with internal septa. Conclusions. Most TDCs in children had echogenicity ranging from hypoechoic to heterogeneous. A thick wall and internal septa were considered to correlate with the presence of inflammation but not with the internal echo patterns of TDCs.

show abstract

“…Physical examination usually reveals a firm, nontender, mobile midline mass located at or below the level of the hyoid bone (61%), which rises with protrusion of the tongue. As many as 25%, however, are located laterally, often on the left (14), and others are intrathyroidal (15), intralingual (2%), suprahyoidal (24%), or suprasternal (13%) (16). There is a large differential diagnosis of central cervical cystic lesions, but the most important are cystic degeneration of a benign colloid nodule or an adenoma, papillary carcinoma, or cystic Hashimoto's thyroiditis in the pyramidal lobe.…”

mentioning

confidence: 93%

Thyroid Cancer in Thyroglossal Duct Remnants: A Diagnostic and Therapeutic Dilemma

Mazzaferri

2004

Thyroid

View full text Add to dashboard Cite

Thyroglossal duct cyst carcinoma: case report and review of the literature, with emphasis on CT findings

Cited by 31 publications

References 9 publications

Diagnosis and treatment of thyroglossal duct carcinoma: Report of three cases with review of literatures

Diagnosis and treatment of thyroglossal duct carcinoma: Report of three cases with review of literatures

Sonographic Assessment of Thyroglossal Duct Cysts in Children

Thyroid Cancer in Thyroglossal Duct Remnants: A Diagnostic and Therapeutic Dilemma

Contact Info

Product

Resources

About